製品の概要

  • 製品名Anti-ARK5 antibody
    ARK5 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ARK5
  • アプリケーション適用あり: ELISA, IHC-P, WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide from the C-terminal region of human ARK5 conjugated to KLH

  • ポジティブ・コントロール
    • Mouse brain tissue lysate and human breast carcinoma tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab71814 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/1000.
IHC-P 1/50 - 1/100.
WB 1/100 - 1/500. Detects a band of approximately 74 kDa (predicted molecular weight: 74 kDa).

ターゲット情報

  • 機能Involved in tolerance to glucose starvation. Phosphorylates ATM. Suppresses Fas-induced apoptosis by phosphorylation of CASP6, thus suppressing the activation of the caspase and the subsequent cleavage of CFLAR.
  • 組織特異性Expressed at high levels in heart and brain, and at lower levels in skeletal muscle, kidney, ovary, placenta, lung and liver.
  • 配列類似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
    Contains 1 protein kinase domain.
  • 翻訳後修飾Ubiquitinated with 'Lys-29'- and 'Lys-33'-linked polyubiquitins which appear to impede LKB1-mediated phosphorylation. Deubiquitinated by USP9X.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AMP activated protein kinase family member 5 antibody
    • AMPK related protein kinase 5 antibody
    • AMPK-related protein kinase 5 antibody
    • NUAK family SNF1 like kinase antibody
    • NUAK family SNF1-like kinase 1 antibody
    • Nuak1 antibody
    • NUAK1_HUMAN antibody
    • Omphalocele kinase 1 antibody
    • Probable serine/threonine protein kinase KIAA0537 antibody
    see all

Anti-ARK5 antibody 画像

  • Anti-ARK5 antibody (ab71814) at 1/100 dilution + mouse brain tissue lysate at 12.5 µg

    Secondary
    HRP-anti-rabbit
    Developed using the ECL technique

    Predicted band size : 74 kDa
    Observed band size : 74 kDa
    Additional bands at : 17 kDa,40 kDa. We are unsure as to the identity of these extra bands.
  • ab71814 at 1/50 dilution, staining ARK5 in human breast carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue, followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-ARK5 antibody (ab71814) 使用論文

ab71814 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"