製品の概要

  • 製品名Anti-ARHGEF9 antibody - C-terminal
    ARHGEF9 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ARHGEF9 - C-terminal
  • アプリケーション適用あり: ELISA, IHC-P, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide from the C-terminal region of human ARHGEF9 conjugated to KLH

  • ポジティブ・コントロール
    • 293 cell lysates transiently transfected with the ARHGEF9 gene. Human brain tissue.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab71350 is purified through a protein A column, followed by peptide affinity purification.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab71350 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/1000.
IHC-P 1/10 - 1/50.
WB 1/50 - 1/100. Detects a band of approximately 55 kDa (predicted molecular weight: 61 kDa).

ターゲット情報

  • 機能Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters.
  • 組織特異性Detected in brain. Detected at low levels in heart.
  • 関連疾患Defects in ARHGEF9 are a cause of startle disease with epilepsy (STHEE) [MIM:300607]; also known as hyperekplexia with epilepsy. Startle disease is a genetically heterogeneous neurologic disorder. STHE is characterized by muscular rigidity of central nervous system origin, particularly in the neonatal period, and by an exaggerated startle response to unexpected acoustic or tactile stimuli.
  • 配列類似性Contains 1 DH (DBL-homology) domain.
    Contains 1 PH domain.
    Contains 1 SH3 domain.
  • 細胞内局在Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 9630036L12Rik antibody
    • A230067K14 antibody
    • ARHG9_HUMAN antibody
    • Arhgef9 antibody
    • Cdc42 guanine nucleotide exchange factor (GEF) 9 antibody
    • Collybistin antibody
    • collybistin I antibody
    • EIEE8 antibody
    • HPEM 2 antibody
    • hPEM-2 collybistin antibody
    • KIAA0424 antibody
    • mKIAA0424 antibody
    • OTTHUMP00000023424 antibody
    • OTTHUMP00000023425 antibody
    • OTTHUMP00000023427 antibody
    • PEM 2 antibody
    • PEM 2 homolog antibody
    • PEM-2 homolog antibody
    • PEM2 antibody
    • Rac/Cdc42 guanine nucleotide exchange factor 9 antibody
    • Rho guanine nucleotide exchange factor 9 antibody
    • RP11 357C3.4 antibody
    • RP23 230K20.3 antibody
    see all

Anti-ARHGEF9 antibody - C-terminal 画像

  • All lanes : Anti-ARHGEF9 antibody - C-terminal (ab71350) at 1/50 dilution

    Lane 1 : Nontransfected 293 cell lysates
    Lane 2 : 293 cell lysates transiently transfected with the ARHGEF9 gene

    Lysates/proteins at 2 µg per lane.


    Predicted band size : 61 kDa
    Observed band size : 55 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 75 kDa (possible non-specific binding).
  • ab71350 at 1/10 dilution, staining ARHGEF9 in human brain by Immunohistochemistry using formalin-fixed, paraffin-embedded tissue, followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-ARHGEF9 antibody - C-terminal (ab71350) 使用論文

This product has been referenced in:
  • Simon S  et al. Inter-kingdom Signaling by the Legionella Quorum Sensing Molecule LAI-1 Modulates Cell Migration through an IQGAP1-Cdc42-ARHGEF9-Dependent Pathway. PLoS Pathog 11:e1005307 (2015). Read more (PubMed: 26633832) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"