製品の概要

  • 製品名Anti-ARHGEF6 antibody
    ARHGEF6 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ARHGEF6
  • アプリケーション適用あり: IPmore details
    適用なし: WB
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chimpanzee, Gorilla
  • 免疫原

    Synthetic peptide, corresponding to a region between residues 726 and 776 of Human ARHGEF6 (NP_004831.1).

  • ポジティブ・コントロール
    • Jurkat whole cell lysates

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: Tris citrate/phosphate, pH 7-8
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab91572 was affinity purified using an epitope specific to ARHGEF6 immobilized on solid support.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab91572 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP
  • 追加情報IP: Use at 5-15 µg/mg of lysate.

    Is unsuitable for WB.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Acts as a RAC1 guanine nucleotide exchange factor (GEF).
    • 組織特異性Ubiquitous.
    • 関連疾患Defects in ARHGEF6 are the cause of mental retardation X-linked type 46 (MRX46) [MIM:300436]. Mental retardation is a mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.
    • 配列類似性Contains 1 CH (calponin-homology) domain.
      Contains 1 DH (DBL-homology) domain.
      Contains 1 PH domain.
      Contains 1 SH3 domain.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Alpha Pix antibody
      • Alpha-Pix antibody
      • ARHG6_HUMAN antibody
      • ARHGEF6 antibody
      • COOL 2 antibody
      • COOL-2 antibody
      • COOL2 antibody
      • Mental retardation, X linked 46 antibody
      • MRX46 antibody
      • PAK interacting exchange factor alpha antibody
      • PAK-interacting exchange factor alpha antibody
      • PIXA antibody
      • Rac/Cdc42 guanine exchange factor (GEF) 6 antibody
      • Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 antibody
      • Rac/Cdc42 guanine nucleotide exchange factor 6 antibody
      • Rho guanine nucleotide exchange factor 6 antibody
      see all

    Anti-ARHGEF6 antibody 画像

    • Detection of ARHGEF6 by Western Blot of Immunprecipitate.
      anti-ARHGEF6, at 1 µg/ml, staining ARHGEF6 in Jurkat whole cell lysate immunoprecipitated using ab91572 at 10 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
      Detection: Chemiluminescence with exposure time of 10 seconds.

    Anti-ARHGEF6 antibody (ab91572) 使用論文

    ab91572 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab91572.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"