製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to ARHGEF14
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 54-307 of Human ARHGEF14 (NP_001106203).

  • ポジティブ・コントロール
    • Molt-4 and Raji whole cell lysates; 293T, A431, H1299, HeLa and HepG2 cell lysates

法規制情報

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab96395 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 128 kDa.

ターゲット情報

  • 機能
    Guanine nucleotide exchange factor that potentially links pathways that signal through RAC1, RHOA and CDC42. Catalyzes guanine nucleotide exchange on RHOA and CDC42 and interacts specifically with the GTP-bound form of RAC1, suggesting that it functions as an effector of RAC1. May also participate in axonal transport in the brain. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42.
  • 配列類似性
    Belongs to the MCF2 family.
    Contains 1 CRAL-TRIO domain.
    Contains 1 DH (DBL-homology) domain.
    Contains 1 PH domain.
    Contains 1 SH3 domain.
    Contains 1 spectrin repeat.
  • ドメイン
    The CRAL-TRIO domain is involved in interaction with inositol phospholipids.
    The DH domain is involved in interaction with CCPG1.
  • 細胞内局在
    Cytoplasm. Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ARHGEF 14 antibody
    • DBL''s big sister antibody
    • DBS antibody
    • FLJ12122 antibody
    • Guanine nucleotide exchange factor DBS antibody
    • KIAA0362 antibody
    • MCF 2L antibody
    • MCF.2 cell line derived transforming sequence like antibody
    • MCF.2 transforming sequence-like antibody
    • MCF2 like protein antibody
    • MCF2 transforming sequence like protein antibody
    • MCF2-transforming sequence-like protein antibody
    • Mcf2l antibody
    • MCF2L_HUMAN antibody
    • OST antibody
    • OST oncogene antibody
    see all

Anti-ARHGEF14 antibody 画像

  • All lanes : Anti-ARHGEF14 antibody (ab96395) at 1/1000 dilution

    Lane 1 : Molt-4 whole cell lysate
    Lane 2 : Raji whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 128 kDa

プロトコール

Anti-ARHGEF14 antibody (ab96395) 使用論文

ab96395 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab96395.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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