製品の概要

  • 製品名Anti-ARHGEF14 antibody
    ARHGEF14 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to ARHGEF14
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment: GTELAETELP NDVQSTSSVL CAHTEKKDKA KEDLRLALKE GHSVLESLRE LQAEGSEPSV NQDQLDNQAT VQRLLAQLNE TEAAFDEFWA KHQQKLEQCL , corresponding to amino acids 220-320 of Human ARHGEF14

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG1
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab57401 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
IHC-P
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 1 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Guanine nucleotide exchange factor that potentially links pathways that signal through RAC1, RHOA and CDC42. Catalyzes guanine nucleotide exchange on RHOA and CDC42 and interacts specifically with the GTP-bound form of RAC1, suggesting that it functions as an effector of RAC1. May also participate in axonal transport in the brain. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42.
    • 配列類似性Belongs to the MCF2 family.
      Contains 1 CRAL-TRIO domain.
      Contains 1 DH (DBL-homology) domain.
      Contains 1 PH domain.
      Contains 1 SH3 domain.
      Contains 1 spectrin repeat.
    • ドメインThe CRAL-TRIO domain is involved in interaction with inositol phospholipids.
      The DH domain is involved in interaction with CCPG1.
    • 細胞内局在Cytoplasm. Cell membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • ARHGEF 14 antibody
      • DBL''s big sister antibody
      • DBS antibody
      • FLJ12122 antibody
      • Guanine nucleotide exchange factor DBS antibody
      • KIAA0362 antibody
      • MCF 2L antibody
      • MCF.2 cell line derived transforming sequence like antibody
      • MCF.2 transforming sequence-like antibody
      • MCF2 like protein antibody
      • MCF2 transforming sequence like protein antibody
      • MCF2-transforming sequence-like protein antibody
      • Mcf2l antibody
      • MCF2L_HUMAN antibody
      • OST antibody
      • OST oncogene antibody
      see all

    Anti-ARHGEF14 antibody 画像

    • ARHGEF14 antibody (ab57401) used in immunohistochemistry at 1ug/ml on formalin fixed and paraffin embedded human tonsil.
    • Western blot against tagged recombinant protein immunogen using ab57401 ARHGEF14 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    Anti-ARHGEF14 antibody (ab57401) 使用論文

    ab57401 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab57401.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"