Rabbit polyclonal to ARHGEF11
This antibody detects endogenous levels of total ARHGEF11 protein.
Synthetic peptide derived from the N terminal region of Human ARHGEF11.
A549 and COLO cell extracts.
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Preservative: 0.02% Sodium azide Constituents: PBS, 0.88% Sodium chloride, 50% Glycerol Note: PBS without Mg2+ and Ca2+
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Immunogen affinity purified
ab110059 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Predicted molecular weight: 168 kDa.
May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13.
Contains 1 DH (DBL-homology) domain.
Contains 1 PDZ (DHR) domain. Contains 1 PH domain. Contains 1 RGSL (RGS-like) domain.
The poly-Pro region is essential for plasma membrane localization upon stimulation.
Cytoplasm. Membrane. Translocated to the membrane upon stimulation.
Information by UniProt
ARHGEF 11 antibody
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