Rabbit polyclonal to ARHGEF11
This antibody detects endogenous levels of total ARHGEF11 protein.
Synthetic peptide derived from the N terminal region of Human ARHGEF11.
A549 and COLO cell extracts.
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Preservative: 0.02% Sodium azide Constituents: PBS, 0.88% Sodium chloride, 50% Glycerol Note: PBS without Mg2+ and Ca2+
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Immunogen affinity purified
ab110059 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Predicted molecular weight: 168 kDa.
May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13.
Contains 1 DH (DBL-homology) domain.
Contains 1 PDZ (DHR) domain. Contains 1 PH domain. Contains 1 RGSL (RGS-like) domain.
The poly-Pro region is essential for plasma membrane localization upon stimulation.
Cytoplasm. Membrane. Translocated to the membrane upon stimulation.
Information by UniProt
ARHGEF 11 antibody
has not yet been referenced specifically in any publications.
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