Anti-Argininosuccinate Lyase 抗体 (ab67512)

製品の概要

  • 製品名Anti-Argininosuccinate Lyase antibody
    Argininosuccinate Lyase 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to Argininosuccinate Lyase
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length argininosuccinate lyase protein (Human)

  • ポジティブ・コントロール
    • Argininosuccinate Lyase transfected 293T cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab67512 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 52 kDa (predicted molecular weight: 52 kDa).

ターゲット情報

  • パスウェイAmino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3.
    Nitrogen metabolism; urea cycle; L-arginine and fumarate from (N(omega)-L-arginino)succinate: step 1/1.
  • 関連疾患Defects in ASL are the cause of arginosuccinicaciduria (ARGINSA) [MIM:207900]. Arginosuccinicaciduria is an autosomal recessive disorder of the urea cycle. The disease is characterized by mental and physical retardation, liver enlargement, skin lesions, dry and brittle hair showing trichorrhexis nodosa microscopically and fluorescing red, convulsions, and episodic unconsciousness.
  • 配列類似性Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
  • 翻訳後修飾Acetylation modifies enzyme activity in response to alterations of extracellular nutrient availability. Acetylation increased with trichostin A (TSA) or with nicotinamide (NAM). Glucose increases acetylation by about a factor of 3 with decreasing enzyme activity. Acetylation on Lys-288 is decreased on the addition of extra amino acids resulting in activation of enzyme activity.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Argininosuccinase antibody
    • Argininosuccinate lyase antibody
    • Arginosuccinase antibody
    • ARLY_HUMAN antibody
    • ASAL antibody
    • ASL antibody
    • EC 4.3.2.1 antibody
    see all

Anti-Argininosuccinate Lyase antibody 画像

  • All lanes : Anti-Argininosuccinate Lyase antibody (ab67512) at 1/500 dilution

    Lane 1 : Argininosuccinate Lyase transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate secondary antibody at 1/2500 dilution

    Predicted band size : 52 kDa
    Observed band size : 52 kDa

Anti-Argininosuccinate Lyase antibody (ab67512) 使用論文

ab67512 has not yet been referenced specifically in any publications.

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