製品の概要

  • 製品名Anti-ARFGAP3 antibody
    ARFGAP3 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to ARFGAP3
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse
    交差が予測される動物種: Rat, Dog, Human
  • 免疫原

    Synthetic peptide:

    C-NGVVTSIQDRYGS

    , corresponding to C terminal amino acids 504-516 of Human ARFGAP3 (Peptide available as ab22801.)

  • 特記事項Principal Names: ARFGAP1, ADP ribosylation factor GTPase activating protein 1, ARFGAP3. GenBank Accession Number: NP055385 LocusLink ID: 26286


    ARFs are critical in vesicular trafficking pathway.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab1308 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 3 µg/ml. Can be blocked with Human ARFGAP3 peptide (ab22801).

Approx 55-60kDa band seen in Mouse Brain extracts.

ターゲット情報

  • 機能GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.
  • 組織特異性Widely expressed. Highest expression in endocrine glands (pancreas, pituitary gland, salivary gland, and prostate) and testis with a much higher expression in the testis than in the ovary.
  • 配列類似性Contains 1 Arf-GAP domain.
  • 発生段階Expressed at higher level in adult thymus, brain and lung, than in corresponding fetal tissues. Expressed at lower level in spleen, heart, kidney and liver during development.
  • 細胞内局在Cytoplasm. Golgi apparatus membrane. Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ADP ribosylation factor GTPase activating protein 1 antibody
    • ADP ribosylation factor GTPase activating protein 3 antibody
    • ADP-ribosylation factor GTPase-activating protein 3 antibody
    • ARF GAP 3 antibody
    • ARFG3_HUMAN antibody
    • ArfGAP 3 antibody
    • ARFGAP1 antibody
    • ARFGAP3 antibody
    • FLJ45618 antibody
    see all

Anti-ARFGAP3 antibody 画像

  • ARFGAP3 staining (2µg/ml) of Mouse Brain extracts (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence

Anti-ARFGAP3 antibody (ab1308) 使用論文

ab1308 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"