製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to Aquaporin 9
  • 特異性
    The 18 AA peptide was found to be unique to Aquaporin 9 without significant homology to any other aquaporins. It has 72% homology with human Aquaporin 9. Aquaporin 9 from other species are yet to be cloned.
  • アプリケーション
    適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Rat
  • 免疫原

    An 18 AA synthetic peptide within the C-terminal domain of rat Aquaporin 9. This domain is predicted to be cytoplasmic (unfortunately, the amino acid sequence is considered to be commercially sensitive).

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    Preservative: None
    Constituents: 40% Glycerol
  • 精製度
    Whole antiserum
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab15127 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報
    ELISA: 1/10,000 - 1/50,000, or 0.5-1 ug/ml for affinity purified antibody. Control peptide can be used to coat ELISA plates at 1 ug/ml.
    WB: 1/1000 - 1/5000, or 1-10 ug/ml for affinity purified antibody using ECL. Predicted molecular weight: 35.4 kDa.
    Immunohistochemistry & Immunofluorescence: Neat serum can be used at 1:500 or more.

    Control peptides, because of their low MW (<3kD), are not suitable for Western. It should be used for ELISA or antibody blocking to confirm antibody specificity

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Forms a channel with a broad specificity. Mediates passage of a wide variety of non-charged solutes including carbamides, polyols, purines, and pyrimidines in a phloretin- and mercury-sensitive manner, whereas amino acids, cyclic sugars, Na(+), K(+), Cl(-), and deprotonated monocarboxylates are excluded. Also permeable to urea and glycerol.
    • 組織特異性
      Highly expressed in peripheral leukocytes. Also expressed in liver, lung, and spleen.
    • 配列類似性
      Belongs to the MIP/aquaporin (TC 1.A.8) family.
    • ドメイン
      Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
    • 細胞内局在
      Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • AQP 9 antibody
      • AQP-9 antibody
      • Aqp9 antibody
      • AQP9_HUMAN antibody
      • Aquaglyceroporin-9 antibody
      • Aquaporin-9 antibody
      • Aquaporin9 antibody
      • HsT 17287 antibody
      • HsT17287 antibody
      • Small solute channel 1 antibody
      • SSC 1 antibody
      • SSC1 antibody
      see all

    プロトコール

    Anti-Aquaporin 9 antibody (ab15127) 使用論文

    This product has been referenced in:
    • Sun Z  et al. Recombinant hirudin treatment modulates aquaporin-4 and aquaporin-9 expression after intracerebral hemorrhage in vivo. Mol Biol Rep 36:1119-27 (2009). WB, IF, IHC ; Rat . Read more (PubMed: 18574711) »

    See 1 Publication for this product

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    We currently have no matching products to the rat extracelluar dom...

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    This antibody recognizes Aquaporin 9. There is no significant sequence homology to any other AQPs. Species Crossreactivity: Human, mouse and rat. Species Sequence Homology: Mouse: 94%; human: 72%. For a polyclonal =70% is usually good enough to ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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