Anti-Aquaporin 4 抗体 (ab15118)

製品の概要

  • 製品名Anti-Aquaporin 4 antibody
    Aquaporin 4 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Aquaporin 4
  • 特異性The 17 AA rat AQP41 peptide was found to be unique to AQP4.
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Rat
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide (Rat) conjugated to KLH (C terminal).

  • ポジティブ・コントロール
    • Rat cerebellum.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab15118 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報ELISA: 1/10000 - 1/50000.
    WB: 1/1000 - 1/5000. Predicted molecular weight: 35 kDa. Note: Recommend the use of 0.5-1% milk in all primary/secondary antibody-enzyme conjugate incubations in order to suppress non-specific bands.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.
    • 組織特異性Brain - muscle >> heart, kidney, lung, and trachea.
    • 配列類似性Belongs to the MIP/aquaporin (TC 1.A.8) family.
    • ドメインAquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
    • 翻訳後修飾Phosphorylation by PKC at Ser-180 reduces conductance by 50%. Phosphorylation by PKG at Ser-111 in response to glutamats increases conductance by 40%.
    • 細胞内局在Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • AQP 4 antibody
      • AQP-4 antibody
      • AQP4 antibody
      • AQP4_HUMAN antibody
      • Aquaporin type 4 antibody
      • Aquaporin-4 antibody
      • Aquaporin4 antibody
      • HMIWC 2 antibody
      • HMIWC2 antibody
      • Mercurial insensitive water channel antibody
      • Mercurial-insensitive water channel antibody
      • MGC22454 antibody
      • MIWC antibody
      • WCH 4 antibody
      • WCH4 antibody
      see all

    Anti-Aquaporin 4 antibody (ab15118) 使用論文

    ab15118 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your enquiry. I can't find any reference to a glycosylated 52KD form. I checked with our source for this antibody and he said he did not either; he "found literature on the Internet that glycosylation of Aquaporin 4 can occur at a motif n...

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    Dear Dr Lovatt; Thank you for your enquiry. We do not have any specific information regarding the epitope that this product recognises. The aa sequence indicates an intracellular epitope. If you need any further assistance please do not hesitate to ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"