Anti-Apoptosis inhibitor 5 抗体 (ab65068)


  • 製品名Anti-Apoptosis inhibitor 5 antibody
    Apoptosis inhibitor 5 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Apoptosis inhibitor 5
  • アプリケーション適用あり: ELISA, IHC-P, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide derived from C-terminus of human Apoptosis inhibitor 5

  • ポジティブ・コントロール
    • Human heart tissue, extracts from 293, Jurkat and HUVEC cells.



Our Abpromise guarantee covers the use of ab65068 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/20000.
IHC-P 1/50 - 1/100.
WB 1/500 - 1/1000. Detects a band of approximately 58 kDa (predicted molecular weight: 58 kDa).


  • 機能Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.
  • 組織特異性Expressed in all tissues tested, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highest levels in heart, pancreas and placenta. Highly expressed in several cancers. Preferentially expressed in squamous cell carcinoma versus adenocarcinoma in non-small cell lung cancer.
  • 配列類似性Belongs to the API5 family.
  • ドメインTwo regions, an N-terminal (aa 96-107) and a C-terminal (aa 274-311) are required for binding FGF2.
  • 細胞内局在Cytoplasm and Nucleus. Cytoplasm. Mainly nuclear. Can also be cytoplasmic.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AAC 11 antibody
    • AAC-11 antibody
    • AAC11 antibody
    • Antiapoptosis clone 11 protein antibody
    • API 5 antibody
    • API-5 antibody
    • api5 antibody
    • API5 like 1 antibody
    • API5_HUMAN antibody
    • API5L1 antibody
    • Apoptosis inhibitor 5 antibody
    • Cell migration inducing gene 8 protein antibody
    • Cell migration-inducing gene 8 protein antibody
    • Fibroblast growth factor 2 interacting factor 2 antibody
    • Fibroblast growth factor 2-interacting factor antibody
    • FIF antibody
    • MIG 8 antibody
    • MIG8 antibody
    • Migration inducing protein MIG8 antibody
    • Protein XAGL antibody
    see all

Anti-Apoptosis inhibitor 5 antibody 画像

  • All lanes : Anti-Apoptosis inhibitor 5 antibody (ab65068) at 1/500 dilution

    Lane 1 : extracts from 293 cells
    Lane 2 : extracts from Jurkat cells
    Lane 3 : extracts from HuvEc cells
    Lane 4 : extracts from HuvEc cells with immunizing peptide at 5 µg

    Lysates/proteins at 5 µg per lane.

    Predicted band size : 58 kDa
    Observed band size : 58 kDa
    Additional bands at : 26 kDa,65 kDa. We are unsure as to the identity of these extra bands.
  • ab65068 at 1/50 dilution staining human heart tissue without (left) and with (right) immunzing peptide; paraffin embedded.

Anti-Apoptosis inhibitor 5 antibody (ab65068) 使用論文

ab65068 has not yet been referenced specifically in any publications.

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