製品の概要

  • 製品名Anti-Apoptosis inhibitor 5 antibody
    Apoptosis inhibitor 5 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to Apoptosis inhibitor 5
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 400-504 of Human Apoptosis inhibitor 5

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab56392 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
IHC-P
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.
    • 組織特異性Expressed in all tissues tested, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highest levels in heart, pancreas and placenta. Highly expressed in several cancers. Preferentially expressed in squamous cell carcinoma versus adenocarcinoma in non-small cell lung cancer.
    • 配列類似性Belongs to the API5 family.
    • ドメインTwo regions, an N-terminal (aa 96-107) and a C-terminal (aa 274-311) are required for binding FGF2.
    • 細胞内局在Cytoplasm and Nucleus. Cytoplasm. Mainly nuclear. Can also be cytoplasmic.
    • Information by UniProt
    • 参照データベース
    • 別名
      • AAC 11 antibody
      • AAC-11 antibody
      • AAC11 antibody
      • Antiapoptosis clone 11 protein antibody
      • API 5 antibody
      • API-5 antibody
      • api5 antibody
      • API5 like 1 antibody
      • API5_HUMAN antibody
      • API5L1 antibody
      • Apoptosis inhibitor 5 antibody
      • Cell migration inducing gene 8 protein antibody
      • Cell migration-inducing gene 8 protein antibody
      • Fibroblast growth factor 2 interacting factor 2 antibody
      • Fibroblast growth factor 2-interacting factor antibody
      • FIF antibody
      • MIG 8 antibody
      • MIG8 antibody
      • Migration inducing protein MIG8 antibody
      • Protein XAGL antibody
      see all

    Anti-Apoptosis inhibitor 5 antibody 画像

    • Apoptosis inhibitor 5 antibody (ab56392) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human small Intestine.


    • Predicted band size : 58 kDa

    Anti-Apoptosis inhibitor 5 antibody (ab56392) 使用論文

    This product has been referenced in:
    • Garcia-Jove Navarro M  et al. Api5 contributes to E2F1 control of the G1/S cell cycle phase transition. PLoS One 8:e71443 (2013). WB . Read more (PubMed: 23940755) »
    • Schlundt A  et al. Proline-rich sequence recognition: II. Proteomics analysis of Tsg101 ubiquitin-E2-like variant (UEV) interactions. Mol Cell Proteomics 8:2474-86 (2009). Read more (PubMed: 19542561) »

    See all 2 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"