製品の概要

  • 製品名Anti-Apolipoprotein L 1 antibody
    Apolipoprotein L 1 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Apolipoprotein L 1
  • 特異性ab116607 is expected to recognize all three reported isoforms (NP_003652.2; NP_663318.1; NP_001130013.1). Reported variants represent identical protein: NP_003652.2, NP_001130012.1.
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide:

    PHASASRPRVTEP

    with a Cysteine residue linker, corresponding to internal sequence amino acids 297-309 of Human Apolipoprotein L 1 (NP_003652.2; NP_663318.1; NP_001130013.1).

  • ポジティブ・コントロール
    • Human Placenta lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab116607 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 42,45 kDa (predicted molecular weight: 42,46 kDa).

ターゲット情報

  • 機能May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver.
  • 組織特異性Plasma. Found on APOA-I-containing high density lipoprotein (HDL3). Expressed in pancreas, lung, prostate, liver, placenta and spleen.
  • 関連疾患Defects in APOL1 are the cause of focal segmental glomerulosclerosis type 4 (FSGS4) [MIM:612551]. It is a renal pathology defined by the presence of segmental sclerosis in glomeruli and resulting in proteinuria, reduced glomerular filtration rate and edema. Renal insufficiency often progresses to end-stage renal disease, a highly morbid state requiring either dialysis therapy or kidney transplantation.
  • 配列類似性Belongs to the apolipoprotein L family.
  • 翻訳後修飾Phosphorylation sites are present in the extracelllular medium.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • APO L antibody
    • Apo-L antibody
    • ApoL antibody
    • APOL I antibody
    • ApoL-I antibody
    • APOL1 antibody
    • APOL1_HUMAN antibody
    • APOLI antibody
    • Apolipoprotein L antibody
    • Apolipoprotein L I antibody
    • Apolipoprotein L-I antibody
    • Apolipoprotein L1 antibody
    • FSGS4 antibody
    see all

Anti-Apolipoprotein L 1 antibody 画像

  • Anti-Apolipoprotein L 1 antibody (ab116607) at 0.1 µg/ml + Human Placenta lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 42,46 kDa

Anti-Apolipoprotein L 1 antibody (ab116607) 使用論文

ab116607 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab116607.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"