製品の概要

  • 製品名
    Anti-Apolipoprotein CIII antibody (HRP)
    Apolipoprotein CIII 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Apolipoprotein CIII (HRP)
  • 標識
    HRP
  • 特異性
    Specifically binds to human Apolipoprotein CIII.
  • アプリケーション
    適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length native APO CIII protein (purified) (Human)

  • 特記事項


    The antibody can be used for detection of human apo CIII in plasma, immunoassays and immunoblots.

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab27624 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/1500 - 1/6000.
WB 1/1500 - 1/6000. Predicted molecular weight: 11 kDa.

The antibody can be used to detect human Apolipoprotein CI in plasma, immunoassays and immunoblots.

ターゲット情報

  • 機能
    Inhibits lipoprotein lipase and hepatic lipase and decreases the uptake of lymph chylomicrons by hepatic cells. This suggests that it delays the catabolism of triglyceride-rich particles.
  • 組織特異性
    Constitutes 50% of the protein fraction of VLDL and 2% of that of HDL. Synthesized predominantly in liver and to a lesser degree in intestine.
  • 関連疾患
    Defects in APOC3 may be a cause of hyperalphalipoproteinemia (HYPALIP) [MIM:143470]. Affected individuals show high levels of alpha-lipoprotein (high density lipoprotein/HDL).
  • 配列類似性
    Belongs to the apolipoprotein C3 family.
  • 翻訳後修飾
    O-linked glycan consists of Gal-GalNAc disaccharide, further modified with up to 3 sialic acid residues. O-glycosylated on Thr-94 with a core 1 or possibly core 8 glycan.
  • 細胞内局在
    Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • APOC3 antibody
    • APO C3 antibody
    • Apo CIII antibody
    • Apo-CIII antibody
    • APOC 3 antibody
    • ApoC III antibody
    • ApoC-III antibody
    • APOC3 antibody
    • APOC3_HUMAN antibody
    • ApoCIII antibody
    • Apolipoprotein C III antibody
    • Apolipoprotein C-III antibody
    • Apolipoprotein C3 antibody
    • ApolipoproteinCIII antibody
    • MGC150353 antibody
    see all

プロトコール

参考文献

This product has been referenced in:
  • Mak AC  et al. Effects of the absence of apolipoprotein e on lipoproteins, neurocognitive function, and retinal function. JAMA Neurol 71:1228-36 (2014). Read more (PubMed: 25111166) »
  • Park KH  et al. Senescence-related truncation and multimerization of apolipoprotein A-I in high-density lipoprotein with an elevated level of advanced glycated end products and cholesteryl ester transfer activity. J Gerontol A Biol Sci Med Sci 65:600-10 (2010). Sandwich ELISA . Read more (PubMed: 20421239) »

See all 3 Publications for this product

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