Anti-Apolipoprotein CIII 抗体 - Aminoterminal end (ab55984)


  • 製品名
    Anti-Apolipoprotein CIII antibody - Aminoterminal end
    Apolipoprotein CIII 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Apolipoprotein CIII - Aminoterminal end
  • アプリケーション
    適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat
  • 免疫原

    Synthetic peptide corresponding to N-terminal residues of mouse Apolipoprotein CIII



Our Abpromise guarantee covers the use of ab55984 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
  • 追加情報
    ELISA: Use at an assay dependent dilution.
    WB: Use at an assay dependent concentration. Predicted molecular weight: 11 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Inhibits lipoprotein lipase and hepatic lipase and decreases the uptake of lymph chylomicrons by hepatic cells. This suggests that it delays the catabolism of triglyceride-rich particles.
    • 組織特異性
      Constitutes 50% of the protein fraction of VLDL and 2% of that of HDL. Synthesized predominantly in liver and to a lesser degree in intestine.
    • 関連疾患
      Defects in APOC3 may be a cause of hyperalphalipoproteinemia (HYPALIP) [MIM:143470]. Affected individuals show high levels of alpha-lipoprotein (high density lipoprotein/HDL).
    • 配列類似性
      Belongs to the apolipoprotein C3 family.
    • 翻訳後修飾
      O-linked glycan consists of Gal-GalNAc disaccharide, further modified with up to 3 sialic acid residues. O-glycosylated on Thr-94 with a core 1 or possibly core 8 glycan.
    • 細胞内局在
    • Information by UniProt
    • 参照データベース
    • 別名
      • APOC3 antibody
      • APO C3 antibody
      • Apo CIII antibody
      • Apo-CIII antibody
      • APOC 3 antibody
      • ApoC III antibody
      • ApoC-III antibody
      • APOC3 antibody
      • APOC3_HUMAN antibody
      • ApoCIII antibody
      • Apolipoprotein C III antibody
      • Apolipoprotein C-III antibody
      • Apolipoprotein C3 antibody
      • ApolipoproteinCIII antibody
      • MGC150353 antibody
      see all



    This product has been referenced in:
    • Johnson LA  et al. Apolipoprotein E4 Exaggerates Diabetic Dyslipidemia and Atherosclerosis in Mice Lacking the LDL Receptor. Diabetes 60:2285-94 (2011). ELISA ; Mouse . Read more (PubMed: 21810592) »
    • Kawakami A  et al. Apolipoprotein CIII links hyperlipidemia with vascular endothelial cell dysfunction. Circulation 118:731-42 (2008). WB ; Human . Read more (PubMed: 18663085) »

    See all 2 Publications for this product

    レビューと Q&A

    Abcam guarantees this product to work in the species/application used in this Abreview.
    Western blot
    Mouse Tissue lysate - whole (liver)
    Gel Running Conditions
    Non-reduced Denaturing (12%)
    Loading amount
    30 µg
    Blocking step
    Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C

    Abcam user community

    Verified customer

    投稿 Nov 13 2017

    Thank you for contacting us. We currently only have a mouse ELISA kit for Apolipoprotein CIII: ab108811 However, we do have antibodies to each of your targets of interest that can be used in ELISA on mouse samples: Apolipoprotein A I: ab7614 or ab20453...

    Read More

    Thank you for contacting us. Thank you for contacting us. The Anti-Apolipoprotein CIII antibody ab55984 is not exatcly the same as that supplied with the Apolipoprotein CIII Rat/Mouse ELISA Kit (ab108811). The kit uses an antibody directed towards ...

    Read More

    Thank you for your enquiry. ApoC3 is a protein in the liver. A mature apoC3 protein show a molecular mass of ~ 8.8 kDa, but it is sensitive to Thrombin cleavage, in this case, apoC3 results in two small fragment, a n-terminal fragement: residues 1 t...

    Read More

    Thank you for your enquiry. In normolipidaemic individuals, the total plasma ApoCIII level is 0.10 g/l which is mainly HDL-linked. Unfortunately, I am not sure about the level of plasma apoCIII in mice, but I guess it may not be a big difference. ...

    Read More

    Thank you for your enquiry. I can confirm that for WB, over-expressed cell lysate of Apolipoprotein CIII were used at 5ug per lane and the dilution of the antibody is about 1ug/ml. Unfortunately, we do not have any information on the ELISA positive ...

    Read More