製品の概要

  • 製品名Anti-Apolipoprotein A II antibody
    Apolipoprotein A II 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Apolipoprotein A II
  • 特異性Typically less than 1% cross reactivity against other types of apoLipoprotein was detected by ELISA. This antibody reacts with human apoLipoprotein A-II and has negligible cross-reactivity with Type A-I, B, C-I, C-II, C-III, E and J apoLipoproteins.
  • アプリケーション適用あり: Dot blot, ELISA, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length native apoLipoprotein Type A-II (purified).

  • 特記事項This antibody has been used to determine that atherosclerotic lesions in the human aorta contain considerable amounts of lipoproteins. These lipoproteins were observed to be complexed with components of the extracellular matrix (especially LDL and proteoglycans). The role of these matrix-lipoprotein complexes is not entirely clear, however, animal models of atherosclerosis have shown that increased cellular proliferation and increased production of extracellular matrix components occur following injury to the intimal layer of the aorta.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab7615 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Dot blot 1/5000 - 1/10000.
ELISA 1/4000 - 1/8000.
WB Use at an assay dependent dilution.

ターゲット情報

  • 機能May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.
  • 組織特異性Plasma; synthesized in the liver and intestine.
  • 配列類似性Belongs to the apolipoprotein A2 family.
  • 翻訳後修飾Phosphorylation sites are present in the extracelllular medium.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • APO A2 antibody
    • Apo AII antibody
    • Apo-AII antibody
    • APOA 2 antibody
    • ApoA II antibody
    • ApoA-II antibody
    • APOA2 antibody
    • APOA2_HUMAN antibody
    • APOAII antibody
    • Apolipoprotein A II antibody
    • Apolipoprotein A-II(1-76) antibody
    • Apolipoprotein A2 antibody
    • Apolipoprotein AII antibody
    • ApolipoproteinA II antibody
    • OTTHUMP00000032244 antibody
    see all

Anti-Apolipoprotein A II antibody (ab7615) 使用論文

This product has been referenced in:
  • Ye GD  et al. OVOL2, an Inhibitor of WNT Signaling, Reduces Invasive Activities of Human and Mouse Cancer Cells and is Downregulated in Human Colorectal Tumors. Gastroenterology N/A:N/A (2015). Read more (PubMed: 26619963) »
  • Kasthuri RS  et al. Extraordinary apolipoprotein oxidation in chronic hepatitis C and liver cirrhosis. Mol Cell Proteomics : (2007). WB ; Human . Read more (PubMed: 17709793) »

See all 2 Publications for this product

Product Wall

Thank you for your enquiry and your interest in our products. We would like to confirm that this antibody can bind ApoAII in intact HDL particles.

The immunogen is derived from human plasma. So far, it has only been tested for cross-reactivity with human.

17.4 kDa.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"