製品の概要

  • 製品名Anti-Apg3 antibody
    Apg3 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to Apg3
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment: MQNVINTVKG KALEVAEYLT PVLKESKFKE TGVITPEEFV AAGDHLVHHC PTWQWATGEE LKVKAYLPTG KQFLVTKNVP CYKRCKQMEY SDELEAIIEE , corresponding to amino acids 1-101 of Human Apg3

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab56409 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能E2-like enzyme involved in autophagy and mitochondrial homeostasis. Catalyzes the conjugation of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A) to phosphatidylethanolamine (PE). PE-conjugation to ATG8-like proteins is essential for autophagy. Preferred substrate is MAP1LC3A. Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3.
    • 組織特異性Widely expressed, with a highest expression in heart, skeletal muscle, kidney, liver and placenta.
    • 配列類似性Belongs to the ATG3 family.
    • 翻訳後修飾Conjugated to ATG12 at Lys-243. ATG12-conjugation plays a role in regulation of mitochondrial homeostasis and cell death, while it is not involved in PE-conjugation to ATG8-like proteins and autophagy.
    • 細胞内局在Cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 2610016C12Rik antibody
      • Apg 3 antibody
      • APG3 antibody
      • APG3 autophagy 3 like antibody
      • APG3 like antibody
      • APG3, S. cerevisiae, homolog of antibody
      • APG3-like antibody
      • APG3L antibody
      • Apg3p antibody
      • ATG 3 antibody
      • ATG3 antibody
      • ATG3 autophagy related 3 homolog antibody
      • ATG3 autophagy related 3 homolog (S. cerevisiae) antibody
      • ATG3_HUMAN antibody
      • Autophagy 3, S. cerevisiae, homolog of antibody
      • Autophagy Apg3p/Aut1p like antibody
      • autophagy related 3 antibody
      • Autophagy related protein 3 antibody
      • Autophagy-related protein 3 antibody
      • DKFZp564M1178 antibody
      • FLJ22125 antibody
      • hApg3 antibody
      • MGC15201 antibody
      • OTTHUMP00000214547 antibody
      • OTTHUMP00000214548 antibody
      • PC3 96 antibody
      • Protein PC3-96 antibody
      • Ubiquitin-like-conjugating enzyme ATG3 antibody
      see all

    Anti-Apg3 antibody 画像



    • Predicted band size : 36 kDa
      Apg3 antibody (ab56409) at 1ug/lane + Jurkat cell lysate at 25ug/lane.

    Anti-Apg3 antibody (ab56409) 使用論文

    ab56409 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"