製品の概要

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG1
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab57158 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.
    • 組織特異性Expressed at high levels in skeletal muscle and heart; in moderate levels in brain, kidney, and liver; and at low levels in colon, thymus, spleen, small intestine, placenta, lung and peripheral blood leukocyte.
    • パスウェイProtein modification; protein ubiquitination.
    • 配列類似性Belongs to the RING-box family.
      Contains 1 RING-type zinc finger.
    • ドメインThe RING-type zinc finger domain coordinates an additional third zinc ion.
    • 翻訳後修飾Auto-ubiquitinated.
    • 細胞内局在Cytoplasm. Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • ANAPC 11 antibody
      • ANAPC11 antibody
      • Anaphase promoting complex subunit 11 (yeast APC11 homolog) antibody
      • Anaphase promoting complex subunit 11 antibody
      • Anaphase promoting complex subunit 11 homolog (yeast) antibody
      • Anaphase promoting complex subunit 11 homolog antibody
      • Anaphase-promoting complex subunit 11 antibody
      • Apc 11 antibody
      • Apc 11p antibody
      • APC11 anaphase promoting complex subunit 11 homolog (yeast) antibody
      • APC11 anaphase promoting complex subunit 11 homolog antibody
      • APC11 antibody
      • APC11_HUMAN antibody
      • Apc11p antibody
      • Cyclosome subunit 11 antibody
      • Hepatocellular carcinoma associated RING finger protein antibody
      • Hepatocellular carcinoma-associated RING finger protein antibody
      • HSPC 214 antibody
      • HSPC214 antibody
      • MGC882 antibody
      • Yeast APC 11 homolog antibody
      • Yeast APC11 homolog antibody
      see all

    Anti-Apc11 antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab57158 Apc11 antibody at 1ug/ml. Predicted band size of immunogen is 31 kDa

    Anti-Apc11 antibody (ab57158) 使用論文

    ab57158 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab57158.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"