Anti-APAF1 抗体 - C-terminal, prediluted (ab15178)

製品の概要

  • 製品名
    Anti-APAF1 antibody - C-terminal, prediluted
    APAF1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to APAF1 - C-terminal, prediluted
  • 由来種
    Rabbit
  • アプリケーション
    適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide corresponding to Human APAF1 (C terminal).
    Database link: O14727

  • ポジティブ・コントロール
    • IHC-P: Human testis tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab15178 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/1. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Primary antibody incubation for 10 minutes at room temperature.

ターゲット情報

  • 機能
    Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
  • 組織特異性
    Ubiquitous. Highest levels of expression in adult spleen and peripheral blood leukocytes, and in fetal brain, kidney and lung. Isoform 1 is expressed in heart, kidney and liver.
  • 配列類似性
    Contains 1 CARD domain.
    Contains 1 NB-ARC domain.
    Contains 13 WD repeats.
  • ドメイン
    The CARD domain mediates interaction with APIP.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • APAF 1 antibody
    • Apaf-1 antibody
    • APAF_HUMAN antibody
    • Apaf1 antibody
    • Apoptotic peptidase activating factor 1 antibody
    • Apoptotic protease activating factor 1 antibody
    • Apoptotic protease activating factor antibody
    • Apoptotic protease-activating factor 1 antibody
    • CED 4 antibody
    • CED4 antibody
    • KIAA0413 antibody
    see all

画像

  • Formalin-fixed, paraffin-embedded human testis tissue stained for APAF1 using ab15178 in immunohistochemical analysis.

参考文献

ab15178 has not yet been referenced specifically in any publications.

レビューと Q&A

Thank you for your enquiry. Further to correspondence with my colleague I can tell you that the undiluted version of ab15178 has the catalogue code ab46899. The antibody datasheet will be available from Monday morning. You can place your order in t...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録