製品の概要

  • 製品名Anti-APAF1 antibody
    APAF1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to APAF1
  • アプリケーション適用あり: IHC-FoFrmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide derived from C terminal of Apaf-1(Human)

  • ポジティブ・コントロール
    • Testis

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab46899 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-FoFr
  • 追加情報IHC-Fo: 1/200.

    Staining of formalin-fixed tissues requires boiling tissue sections in 10mM
    Citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
    • 組織特異性Ubiquitous. Highest levels of expression in adult spleen and peripheral blood leukocytes, and in fetal brain, kidney and lung. Isoform 1 is expressed in heart, kidney and liver.
    • 配列類似性Contains 1 CARD domain.
      Contains 1 NB-ARC domain.
      Contains 13 WD repeats.
    • ドメインThe CARD domain mediates interaction with APIP.
    • 細胞内局在Cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • APAF 1 antibody
      • Apaf-1 antibody
      • APAF_HUMAN antibody
      • Apaf1 antibody
      • Apoptotic peptidase activating factor 1 antibody
      • Apoptotic protease activating factor 1 antibody
      • Apoptotic protease activating factor antibody
      • Apoptotic protease-activating factor 1 antibody
      • CED 4 antibody
      • CED4 antibody
      • KIAA0413 antibody
      see all

    Anti-APAF1 antibody 画像

    • Human testis stained with ab46899 using the antibody at a dilution of 1:200

    Anti-APAF1 antibody (ab46899) 使用論文

    ab46899 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab46899.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"