The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 5 µg/ml.
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 47 kDa.
Use a concentration of 20 µg/ml.
Use at an assay dependent concentration.
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.
Belongs to the adaptor complexes medium subunit family. Contains 1 MHD (mu homology) domain.
Zhang H et al. Combination of betulinic acid and chidamide inhibits acute myeloid leukemia by suppression of the HIF1a pathway and generation of reactive oxygen species. Oncotarget8:94743-94758 (2017).
Read more (PubMed: 29212263) »
Llinares E et al. The AP-3 adaptor complex mediates sorting of yeast and mammalian PQ-loop-family basic amino acid transporters to the vacuolar/lysosomal membrane. Sci Rep5:16665 (2015).
Read more (PubMed: 26577948) »