製品の概要

  • 製品名Anti-AP2 alpha + beta antibody
    AP2 alpha + beta 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to AP2 alpha + beta
  • 特異性This antibody recognizes both AP2 alpha A (50 kDa) and AP2 alpha B (40 kDa) forms of AP2.
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat, Sheep, Chicken, Xenopus laevis
  • 免疫原

    Synthetic peptide:

    GLDPRRDYRRHEDLL

    , corresponding to amino acids 120-134 of Human AP2 alpha + beta.

  • ポジティブ・コントロール
    • JEG-3 nuclear extract.
  • 特記事項


    The AP2 transcription factors form the OB2 complex that has been shown to up-regulate c-erbB-2 transcription.

法規制情報

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: 0.1% Sodium Azide and 0.01% Thiomerosal.
    Constituents: PBS containing 0.2% Gelatin.
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 一次抗体 備考The AP2 transcription factors form the OB2 complex that has been shown to up-regulate c-erbB-2 transcription.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab11907 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 40, 50 kDa (predicted molecular weight: a=40, b=50 kDa).

ターゲット情報

  • 関連性The AP2 proteins are normally expressed in ectodermally derived vertebrate tissues where they are necessary for normal growth and development. The factors have also been implicated in the control of cell proliferation, viral transformation, and oncogenesis. AP2 seems to play in important role in human breast cancer. AP2 alpha is the only AP2 protein required for early morphogenesis of the lens vesicle. AP2 beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia
  • 細胞内局在Nuclear
  • 参照データベース
  • 別名
    • Activating enhancer binding protein 2 alpha antibody
    • Activating enhancer binding protein 2 beta antibody
    • Activator protein 2 antibody
    • AP 2 antibody
    • AP 2alpha antibody
    • AP 2B antibody
    • AP-2 transcription factor antibody
    • AP2 B antibody
    • AP2-alpha antibody
    • AP2-beta antibody
    • AP2TF antibody
    • BOFS antibody
    • TFAP2 antibody
    • TFAP2A antibody
    • TFAP2B antibody
    • Transcription factor AP2 alpha antibody
    • Transcription factor AP2 beta antibody
    see all

Anti-AP2 alpha + beta antibody 画像



  • Predicted band size : a=40, b=50 kDa


    Detection of AP2 by Western blot analysis. Activator protein 2 (AP2) can be detected in nuclear extracts derived from JEG-3 cells using AP2 rabbit polyclonal antibody at a 1/1000 dilution (lane 1). The signal corresponding to nuclear AP2 is eliminated by adding the immunizing peptide to the reaction (lane 2).

Anti-AP2 alpha + beta antibody (ab11907) 使用論文

This product has been referenced in:
  • Terrand J  et al. LRP1 controls intracellular cholesterol storage and fatty acid synthesis through modulation of Wnt signaling. J Biol Chem 284:381-8 (2009). WB ; Mouse . Read more (PubMed: 18990694) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"