Antimycin A, Antibiotic (ab141904)
Key features and details
- Antibiotic; induces apoptosis
- CAS Number: 1397-94-0
- Purity: > 95%
- Soluble in ethanol to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Streptomyces sp.
製品の概要
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製品名
Antimycin A, Antibiotic -
製品の詳細
Antibiotic; induces apoptosis -
精製度
> 95% -
CAS 番号
1397-94-0 -
構造式
製品の特性
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体系名
[(2R,3S,6S,7R,8R)-3-[(3-Formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylbutanoate (for Antimycin A1: R = C6H13) -
分子量
548.63 -
分子式
C28H40N2O9 (for Antimycin A1, R = C6H13) -
PubChem 登録番号
14957 -
保存方法
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in ethanol to 100 mM and in DMSO to 100 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
CCCCCC[C@@H]1[C@H]([C@@H](OC(=O)[C@H]([C@H](OC1=O)C)NC(=O)C2=C(C(=CC=C2)NC=O)O)C)OC(=O)CC(C)C -
由来
Streptomyces sp.
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (22)
ab141904 は 22 報の論文で使用されています。
- Feng Y et al. Long noncoding RNA uc007nnj.1 mediates neuronal death induced by retinal ischemia/reperfusion in mice via the miR-155-5p/Tle4 axis. Mol Med 29:9 (2023). PubMed: 36653745
- Chen Z et al. Ether phospholipids are required for mitochondrial reactive oxygen species homeostasis. Nat Commun 14:2194 (2023). PubMed: 37069167
- Lin D et al. Hypoxia-induced reprogramming of glucose-dependent metabolic pathways maintains the stemness of human bone marrow-derived endothelial progenitor cells. Sci Rep 13:8776 (2023). PubMed: 37258701
- Li X et al. DsbA-L interacts with VDAC1 in mitochondrion-mediated tubular cell apoptosis and contributes to the progression of acute kidney disease. EBioMedicine 76:103859 (2022). PubMed: 35124430
- Rodríguez-Nuevo A et al. Oocytes maintain ROS-free mitochondrial metabolism by suppressing complex I. Nature 607:756-761 (2022). PubMed: 35859172