Anti-Natriuretic peptides A 抗体 [L11-11-D6-B4] (ab14442)
Key features and details
- Mouse monoclonal [L11-11-D6-B4] to Natriuretic peptides A
- Suitable for: ELISA
- Reacts with: Human
- Isotype: IgG1
製品の概要
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製品名
Anti-Natriuretic peptides A antibody [L11-11-D6-B4]
Natriuretic peptides A 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [L11-11-D6-B4] to Natriuretic peptides A -
由来種
Mouse -
特異性
ab14442 recognizes synthetic Natriuretic peptides A. -
アプリケーション
適用あり: ELISAmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Sheep, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig -
免疫原
Synthetic peptide corresponding to Human Natriuretic peptides A aa 100 to the C-terminus. Poly Lysin conjugated synthetic peptide.
Database link: P01160 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.40
Constituent: 0.79% Tris HCl -
Concentration information loading...
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精製度
Protein G purified -
特記事項(精製)
Cell culture supernatant, Protein G purified. -
ポリ/モノ
モノクローナル -
クローン名
L11-11-D6-B4 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab14442の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
ELISA |
Use at an assay dependent concentration.
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特記事項 |
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ELISA
Use at an assay dependent concentration. |
ターゲット情報
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機能
Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3. -
関連疾患
Atrial standstill 2
Atrial fibrillation, familial, 6 -
配列類似性
Belongs to the natriuretic peptide family. -
翻訳後修飾
Cleaved by CORIN upon secretion to produce the functional hormone.
Atrial natriuretic factor: Cleaved by MME. The cleavage initiates degradation of the factor and thereby regulate its activity. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 281355 Cow
- Entrez Gene: 608289 Dog
- Entrez Gene: 4878 Human
- Entrez Gene: 230899 Mouse
- Entrez Gene: 397496 Pig
- Entrez Gene: 24602 Rat
- Omim: 108780 Human
- SwissProt: Q9GLD0 Cat
see all -
別名
- ANF antibody
- ANF_HUMAN antibody
- ANP antibody
see all
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (1)
ab14442 は 1 報の論文で使用されています。
- Bovill E et al. Induction by left ventricular overload and left ventricular failure of the human Jumonji gene (JARID2) encoding a protein that regulates transcription and reexpression of a protective fetal program. J Thorac Cardiovasc Surg 136:709-16 (2008). PubMed: 18805276