製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to Annexin A2
  • アプリケーション
    適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Recombinant fragment, corresponding to amino acids 177-329 of Human Annexin II (NM_001002857).

  • ポジティブ・コントロール
    • WB: SW480 and MDA-MB-231 cell lysates IHC-P: Human colon carcinoma tissue

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab90643 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/200 - 1/1000. Predicted molecular weight: 38 kDa.
IHC-P 1/50 - 1/200.

ターゲット情報

  • 機能
    Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response.
  • 配列類似性
    Belongs to the annexin family.
    Contains 4 annexin repeats.
  • ドメイン
    A pair of annexin repeats may form one binding site for calcium and phospholipid.
  • 翻訳後修飾
    Phosphorylation of Tyr-24 enhances heat stress-induced translocation to the cell surface.
    ISGylated.
  • 細胞内局在
    Secreted > extracellular space > extracellular matrix > basement membrane. Melanosome. In the lamina beneath the plasma membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Translocated from the cytoplasm to the cell surface through a Golgi-independent mechanism.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Annexin A2 antibody
    • Annexin II antibody
    • Annexin II, heavy chain antibody
    • Annexin-2 antibody
    • ANX 2 antibody
    • ANX2 antibody
    • ANX2L4 antibody
    • ANXA2 antibody
    • ANXA2_HUMAN antibody
    • arylsulfatase B antibody
    • CAL1H antibody
    • Calpactin I heavy chain antibody
    • calpactin I heavy polypeptide (p36) antibody
    • Calpactin I heavy polypeptide antibody
    • Calpactin-1 heavy chain antibody
    • chromobindin 8 antibody
    • Chromobindin-8 antibody
    • Epididymis secretory protein Li 270 antibody
    • HEL S 270 antibody
    • LIP2 antibody
    • Lipocortin II antibody
    • LPC2 antibody
    • LPC2D antibody
    • p36 antibody
    • P36 protein antibody
    • PAP-IV antibody
    • Placental anticoagulant protein IV antibody
    • Protein I antibody
    see all

画像

  • All lanes : Anti-Annexin A2 antibody (ab90643) at 1/500 dilution

    Lane 1 : SW480 cell lysate
    Lane 2 : MDA-MB-231 cell lysate


    Predicted band size : 38 kDa
  • ab90643, at 1/100 dilution, staining Annexin II in formalin fixed, paraffin embedded Human carcinoma tissue by Immunohistochemistry.

参考文献

ab90643 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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