製品の概要

  • 製品名Anti-Annexin A1 antibody
    Annexin A1 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Annexin A1
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Horse, Guinea pig, Cow, Dog, Pig
  • 免疫原

    Synthetic peptide:

    CQAILDETKGDYEK

    , corresponding to C terminal amino acids 324-337 of Human Annexin A1 (NP_000691.1).

  • ポジティブ・コントロール
    • Human Placenta and Prostate tissues; A431 and K562 cell lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab115770 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.5 - 1.5 µg/ml. Detects a band of approximately 35 kDa (predicted molecular weight: 39 kDa).
IHC-P Use a concentration of 4 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity.
  • 配列類似性Belongs to the annexin family.
    Contains 4 annexin repeats.
  • ドメインA pair of annexin repeats may form one binding site for calcium and phospholipid.
  • 翻訳後修飾Phosphorylated by protein kinase C, epidermal growth factor receptor/kinase and TRPM7. Phosphorylation results in loss of the inhibitory activity.
  • 細胞内局在Nucleus. Cytoplasm. Cell projection > cilium. Basolateral cell membrane. Found in the cilium, nucleus and basolateral cell membrane of ciliated cells in the tracheal endothelium (By similarity). Found in the cytoplasm of type II pneumocytes and alveolar macrophages.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Annexin 1 antibody
    • Annexin A1 antibody
    • Annexin I (lipocortin I) antibody
    • Annexin I antibody
    • Annexin-1 antibody
    • AnnexinA1 antibody
    • AnnexinI antibody
    • ANX 1 antibody
    • ANX A1 antibody
    • ANX1 antibody
    • ANXA 1 antibody
    • ANXA1 antibody
    • ANXA1 protein antibody
    • ANXA1_HUMAN antibody
    • Calpactin 2 antibody
    • Calpactin II antibody
    • Calpactin-2 antibody
    • CalpactinII antibody
    • Chromobindin 9 antibody
    • Chromobindin-9 antibody
    • Chromobindin9 antibody
    • HGNC:533 antibody
    • Lipocortin 1 antibody
    • Lipocortin I antibody
    • Lipocortin1 antibody
    • LipocortinI antibody
    • LPC 1 antibody
    • LPC1 antibody
    • p35 antibody
    • Phospholipase A2 inhibitory protein antibody
    see all

Anti-Annexin A1 antibody 画像

  • ab115770, at 4 ug/ml, staining Annexin A1 in Formalin fixed, Paraffin embedded Human placenta by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.
  • ab115770, at 4 ug/ml, staining Annexin A1 in Formalin fixed, Paraffin embedded Human prostate by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen
  • Anti-Annexin A1 antibody (ab115770) at 0.5 µg/ml + A431 lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 39 kDa

Anti-Annexin A1 antibody (ab115770) 使用論文

ab115770 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"