製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to ANKRD17
  • アプリケーション
    適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Guinea pig, Cow, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Bat, Elephant
  • 免疫原

    Synthetic peptide, corresponding to a region between amino acids 1550-1600 of Human ANKRD17 (NP_115593.3, GeneID 26057).

  • ポジティブ・コントロール
    • Human Controls: Breast Carcinoma, Colon Carcinoma, Ovarian Carcinoma, Prostate Carcinoma, Skin Basal Cell Carcinoma, Testicular Seminoma
  • 特記事項
    Immunoglobulin concentration was determined by extinction coefficient: absorbance at 280 nm of 1.4 equals 1.0 mg of IgG.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab105112 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

ターゲット情報

  • 機能
    Could play pivotal roles in cell cycle and DNA regulation (PubMed:19150984). Involved in innate immune defense against viruse by positively regulating the viral dsRNA receptors DDX58 and IFIH1 signaling pathways (PubMed:22328336). Involves in NOD2- and NOD1-mediated responses to bacteria suggesting a role in innate antibacterial immune pathways too (PubMed:23711367). Target of enterovirus 71 which is the major etiological agent of HFMD (hand, foot and mouth disease) (PubMed:17276651). Could play a central role for the formation and/or maintenance of the blood vessels of the circulation system.
  • 組織特異性
    Ubiquitously expressed.
  • 配列類似性
    Contains 25 ANK repeats.
    Contains 1 KH domain.
  • 翻訳後修飾
    Phosphorylated by CDK2.
  • 細胞内局在
    Cytoplasm. Nucleus. Detected around the nucleolus. Localized on chromatin in a cell cycle-dependent manner.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ANKRD 17 antibody
    • ANKRD17 antibody
    • Ankyrin repeat domain protein 17 antibody
    • Ankyrin repeat domain-containing protein 17 antibody
    • ANR17_HUMAN antibody
    • FLJ22206 antibody
    • Gene trap ankyrin repeat antibody
    • Gene trap ankyrin repeat protein antibody
    • GTAR antibody
    • KIAA0697 antibody
    • MASK2 antibody
    • NY BR 16 antibody
    • NY-BR-16 antibody
    • Serologically defined breast cancer antigen NY-BR-16 antibody
    see all

Anti-ANKRD17 antibody 画像

  • ab105112 at 1/250 dilution staining ANKRD17 in Human breast carcinoma by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining
  • ab105112 at 1/250 dilution staining ANKRD17 in Human prostate carcinoma by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining

プロトコール

Anti-ANKRD17 antibody (ab105112) 使用論文

ab105112 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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