製品の概要

  • 製品名Anti-Anillin antibody
    Anillin 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Anillin
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat, Dog
  • 免疫原

    Synthetic peptide:

    C-TYPDDEKRKNP

    , corresponding to internal sequence amino acids 1018-1028 of Human Anillin

  • ポジティブ・コントロール
    • Human or mouse Brain lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab52059 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報Peptide ELISA: Antibody detection limit dilution 1:16,000.
    WB: Use at a concentration of 1.0 - 3.0 µg/ml. Detects a band of approximately 100 kDa (predicted molecular weight: 124 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Required for cytokinesis. Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression.
    • 組織特異性Ubiquitously expressed. Present at highest levels in the brain, at high levels in the placenta and testis, at intermediate levels in the intestine, ovary, skeletal muscle and thymus and at lower levels in heart, kidney, liver, lung, pancreas, prostate and spleen. Overexpressed in many tumor types including breast, colorectal, endometrial, hepatic, kidney, lung, ovarian and pancreatic tumors.
    • 配列類似性Contains 1 PH domain.
    • 発生段階Expressed in fetal brain, heart, kidney, liver, lung, skeletal muscle, spleen and thymus. In dividing cells expression increases during S and G2 phases, peaks at mitosis and subsequently drops as cells enter G1 phase.
    • 翻訳後修飾Phosphorylated during mitosis.
      Ubiquitinated, and this requires FZR1/CDH1.
    • 細胞内局在Nucleus. Cytoplasm > cytoskeleton. Cytoplasm > cell cortex. Mainly found in the nucleus during interphase. Colocalizes with cortical F-actin upon nuclear envelope breakdown in mitosis and subsequently concentrates in the area of the prospective contractile ring in anaphase. This pattern persists until telophase, when the protein becomes concentrated in the midbody.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Actin binding protein scraps homolog Drosophila antibody
      • Actin binding protein anillin antibody
      • Actin-binding protein anillin antibody
      • Anillin actin binding protein antibody
      • anln antibody
      • ANLN_HUMAN antibody
      • DKFZp779A055 antibody
      • Scra antibody
      • Scraps antibody
      • Scraps homolog antibody
      see all

    Anti-Anillin antibody 画像

    Anti-Anillin antibody (ab52059) 使用論文

    ab52059 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"