Anti-Angiotensin II Type 1 Receptor 抗体 (ab59018)


  • 製品名Anti-Angiotensin II Type 1 Receptor antibody
    Angiotensin II Type 1 Receptor 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Angiotensin II Type 1 Receptor
  • 特異性All reported variants represent identical protein (NP_000676.1, NP_004826.2, NP_033611.1, NP_114038.1 and NP_114438.1).
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Rat, Human
    交差が予測される動物種: Sheep, Rabbit, Guinea pig, Cow, Dog, Pig, Chimpanzee
  • 免疫原

    Synthetic peptide:


    , corresponding to internal sequence amino acids 227-240 of Human Angiotensin II Type 1 Receptor

  • ポジティブ・コントロール
    • Mouse Liver lysate.



Our Abpromise guarantee covers the use of ab59018 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
  • 追加情報Peptide ELISA: antibody detection limit dilution 1:32,000.

    WB: Use at a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 41 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
    • 組織特異性Liver, lung, adrenal and adrenocortical adenomas.
    • 関連疾患Defects in AGTR1 are a cause of renal tubular dysgenesis (RTD) [MIM:267430]. RTD is an autosomal recessive severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype).
    • 配列類似性Belongs to the G-protein coupled receptor 1 family.
    • 翻訳後修飾C-terminal Ser or Thr residues may be phosphorylated.
    • 細胞内局在Cell membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • AG2S antibody
      • Agtr 1 antibody
      • Agtr1 antibody
      • AGTR1_HUMAN antibody
      • Agtr1a antibody
      • AGTR1B antibody
      • Ang II antibody
      • Angiotensin II receptor type 1 antibody
      • Angiotensin II type-1 receptor antibody
      • Angiotensin receptor 1 antibody
      • Angiotensin receptor 1B antibody
      • AT 1B antibody
      • AT 1r antibody
      • AT1 antibody
      • At1a antibody
      • AT1AR antibody
      • AT1B antibody
      • AT1BR antibody
      • AT1R antibody
      • AT2R1 antibody
      • AT2R1A antibody
      • AT2R1B antibody
      • HAT1R antibody
      • Type 1 angiotensin II receptor antibody
      • Type 1B angiotensin II receptor antibody
      • Type-1 angiotensin II receptor antibody
      see all

    Anti-Angiotensin II Type 1 Receptor antibody 画像

    • Anti-Angiotensin II Type 1 Receptor antibody (ab59018) at 0.3 µg/ml + Mouse Liver lysate (35µg protein in RIPA buffer)

      Predicted band size : 41 kDa
      Observed band size : 38 kDa (why is the actual band size different from the predicted?)

    Anti-Angiotensin II Type 1 Receptor antibody (ab59018) 使用論文

    This product has been referenced in:
    • Goyal R  et al. Antenatal maternal protein deprivation: sexually dimorphic programming of the pancreatic renin-angiotensin system. J Renin Angiotensin Aldosterone Syst 14:137-45 (2013). Read more (PubMed: 22898440) »

    See 1 Publication for this product

    Product Wall

    Abcam has not validated the combination of species/application used in this Abreview.
    Application Immunocytochemistry/ Immunofluorescence
    Sample Mouse Cell (Kidney)
    Specification Kidney
    Fixative Formaldehyde
    Permeabilization Yes - 0.5% TX100
    Blocking step Serum as blocking agent for 20 minute(s) · Concentration: 5% · Temperature: 25°C

    Herr Dr. Vladimir Milenkovic

    Verified customer

    投稿 Feb 17 2009