製品の概要

  • 製品名
    Amyloid β Peptide (1-28)
  • 製品の詳細
    Amyloidogenic peptide. Amyloid β Peptide (1-28).
  • 生理活性の詳細

    Amyloidogenic peptide. Occupies the extracellular region of amyloid precursor protein, that can form an α-helical or oligomeric β-sheet. Responsible for amyloid conformational variability. Conformational change induced by N-terminal metal binding. Cytotoxic in vitro.

製品の特性

参考文献

This product has been referenced in:
  • Gaggelli E  et al. NMR studies of the Zn2+ interactions with rat and human beta-amyloid (1-28) peptides in water-micelle environment. J Phys Chem B 112:100-9 (2008). Read more (PubMed: 18072760) »
  • Alvarez XA  et al. Intrahippocampal injections of the beta-amyloid 1-28 fragment induces behavioral deficits in rats. Methods Find Exp Clin Pharmacol 19:471-9 (1997). Read more (PubMed: 9413830) »
  • Maneiro E  et al. An experimental model to study the cytotoxic effects induced by beta-amyloid, histamine, LPS and serum from Alzheimer patients on cultured rat endothelial cells. Methods Find Exp Clin Pharmacol 19:5-12 (0). Read more (PubMed: 9098834) »

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