製品の概要

  • 製品名Anti-Amylin antibody
    Amylin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Amylin
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rabbit, Cat, Dog, Baboon
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 1 - 100 of Human Amylin.

  • ポジティブ・コントロール
    • This antibody gave a positive signal in a human pancreas tissue section.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab77387 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

ターゲット情報

  • 機能Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
  • 配列類似性Belongs to the calcitonin family.
  • ドメインThe mature protein is largely unstructured in the absence of a cognate ligand, and has a strong tendency to form fibrillar aggregates. Homodimerization may be the first step of amyloid formation.
  • 翻訳後修飾Amyloid fibrils are degraded by IDE.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Amylin antibody
    • DAP antibody
    • Diabetes associated peptide antibody
    • Diabetes-associated peptide antibody
    • IAP antibody
    • IAPP antibody
    • IAPP_HUMAN antibody
    • Insulinoma amyloid peptide antibody
    • Islet amyloid polypeptide (diabetes associated peptide; amylin) antibody
    • Islet amyloid polypeptide antibody
    see all

Anti-Amylin antibody 画像

  • IHC image of Amylin staining in Human Pancreas section, performed on a BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab77387, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX

Anti-Amylin antibody (ab77387) 使用論文

ab77387 has not yet been referenced specifically in any publications.

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