製品の概要

  • 製品名Anti-Amylin antibody
    Amylin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Amylin
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Human) (N terminal).

  • ポジティブ・コントロール
    • Pancreas.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab15125 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報IHC-P: 1/200 for 10 min at RT. Boil tissue sections in 10mM
    citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min before commencing with IHC staining protocol.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
    • 配列類似性Belongs to the calcitonin family.
    • ドメインThe mature protein is largely unstructured in the absence of a cognate ligand, and has a strong tendency to form fibrillar aggregates. Homodimerization may be the first step of amyloid formation.
    • 翻訳後修飾Amyloid fibrils are degraded by IDE.
    • 細胞内局在Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Amylin antibody
      • DAP antibody
      • Diabetes associated peptide antibody
      • Diabetes-associated peptide antibody
      • IAP antibody
      • IAPP antibody
      • IAPP_HUMAN antibody
      • Insulinoma amyloid peptide antibody
      • Islet amyloid polypeptide (diabetes associated peptide; amylin) antibody
      • Islet amyloid polypeptide antibody
      see all

    Anti-Amylin antibody 画像

    • ab15125 staining Amylin in human pancreas by Immunohistochemistry (Formalin/ PFA fixed paraffin embedded tissue sections).

    Anti-Amylin antibody (ab15125) 使用論文

    This product has been referenced in:
    • Suzuki H & Yamamoto T Amylin-like immunoreactivity in pancreatic X cells of the black-spotted frog Rana (Pelophylax) nigromaculata. Tissue Cell 46:535-9 (2014). IHC-Fr ; Frog . Read more (PubMed: 25458814) »

    See 1 Publication for this product

    Product Wall

    Thank you for your enquiry and your interest in our products.
    Concerning ab18018 - there is significant sequence homology between human amylin and that of mouse and rat, but this antibody has only been tested with human samples.
    Unfortunately...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"