製品の概要

  • 製品名Anti-AMSH antibody
    AMSH 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to AMSH
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 362-391 of Human AMSH (NP_964010.1, NP_998787.1, NP_006454.1).

  • ポジティブ・コントロール
    • A549 cell line lysates, mouse cerebellum tissue lysates

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab113053 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 48 kDa.

ターゲット情報

  • 機能Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Functions at the endosome and is able to oppose the ubiquitin-dependent sorting of receptors to lysosomes. Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7.
  • 組織特異性Ubiquitously expressed.
  • 配列類似性Belongs to the peptidase M67C family.
    Contains 1 MPN (JAB/Mov34) domain.
  • ドメインThe JAMM motif is essential for the protease activity.
  • 翻訳後修飾Phosphorylated after BMP type I receptor activation.
    Ubiquitinated by SMURF2 in the presence of RNF11.
  • 細胞内局在Nucleus. Membrane. Cytoplasm. Early endosome.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AMSH antibody
    • Associated molecule with the SH3 domain of STAM antibody
    • Endosome associated ubiquitin isopeptidase antibody
    • Endosome-associated ubiquitin isopeptidase antibody
    • MGC126516 antibody
    • MGC126518 antibody
    • MICCAP antibody
    • STABP_HUMAN antibody
    • STAM binding protein antibody
    • STAM-binding protein antibody
    • Stambp antibody
    see all

Anti-AMSH antibody 画像

  • Anti-AMSH antibody (ab113053) at 1/100 dilution + A549 cell line lysates at 35 µg

    Predicted band size : 48 kDa
  • Anti-AMSH antibody (ab113053) at 1/100 dilution + Mouse cerebellum tissue lysates at 35 µg

    Predicted band size : 48 kDa

Anti-AMSH antibody (ab113053) 使用論文

ab113053 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab113053.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"