製品の概要

  • 製品名Anti-AMN antibody
    AMN 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to AMN
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Horse, Guinea pig, Cow, Dog, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 35-84 (NWSQNRTPCA GGAVEFPADK MVSVLVQEGH AVSDMLLPLD GELVLASGAG) of Human AMN (NP_112205).

  • ポジティブ・コントロール
    • Human fetal liver lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab105806 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 46 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Necessary for efficient absorption of vitamin B12. May direct the production of trunk mesoderm during development by modulating a bone morphogenetic protein (BMP) signaling pathway in the underlying visceral endoderm.
  • 組織特異性Long isoforms are highly expressed in small intestine, colon and kidney (renal proximal tubule epithelial cells). Shorter isoforms are detected at lower levels in testis, thymus and peripheral blood leukocytes.
  • 関連疾患Defects in AMN are a cause of recessive hereditary megaloblastic anemia 1 (RH-MGA1) [MIM:261100]; also known as MGA1 Norwegian type or Imerslund-Grasbeck syndrome (I-GS). RH-MGA1 is due to selective malabsorption of vitamin B12. Defects in vitamin B12 absorption lead to impaired function of thymidine synthase. As a consequence DNA synthesis is interrupted. Rapidly dividing cells involved in erythropoiesis are particularly affected.
  • 配列類似性Contains 1 VWFC domain.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 5033428N14Rik antibody
    • amn antibody
    • Amnion associated transmembrane protein antibody
    • Amnionless antibody
    • Amnionless homolog antibody
    • AMNLS_HUMAN antibody
    • AV002116 antibody
    • PRO1028 antibody
    • Protein amnionless antibody
    • Type I transmembrane protein antibody
    • UNQ513/PRO1028 antibody
    • Visceral endoderm specific type 1 transmembrane protein antibody
    see all

Anti-AMN antibody 画像

  • Anti-AMN antibody (ab105806) at 1 µg/ml + Human fetal liver lysate at 10 µg

    Predicted band size : 46 kDa

Anti-AMN antibody (ab105806) 使用論文

ab105806 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab105806.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"