製品の概要

  • 製品名Anti-Aminoacylase 1 antibody
    Aminoacylase 1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to Aminoacylase 1
  • アプリケーション適用あり: WB, ICC/IF, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-409 of Human Aminoacylase 1

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab54960 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ICC/IF
IHC-P
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.
    IF/ICC: Use at a concentration of 10 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate).
    • 組織特異性Expression is highest in kidney, strong in brain and weaker in placenta and spleen.
    • 関連疾患Defects in ACY1 are the cause of aminoacylase-1 deficiency (ACY1D) [MIM:609924]. ACY1D results in a metabolic disorder manifesting with encephalopathy, unspecific psychomotor delay, psychomotor delay with atrophy of the vermis and syringomyelia, marked muscular hypotonia or normal clinical features. Epileptic seizures are a frequent feature. All affected individuals exhibit markedly increased urinary excretion of several N-acetylated amino acids.
    • 配列類似性Belongs to the peptidase M20A family.
    • 細胞内局在Cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • ACY 1 antibody
      • ACY-1 antibody
      • Acy1 antibody
      • ACY1_HUMAN antibody
      • ACY1D antibody
      • ACYLASE antibody
      • Acylase I antibody
      • Aminoacylase-1 antibody
      • EC 3.5.1.14 antibody
      • epididymis secretory protein Li 5 antibody
      • HEL-S-5 antibody
      • N acyl L amino acid amidohydrolase antibody
      • N-acyl-L-amino-acid amidohydrolase antibody
      • OTTHUMP00000212459 antibody
      • OTTHUMP00000212462 antibody
      • OTTHUMP00000212463 antibody
      • OTTHUMP00000212464 antibody
      • OTTHUMP00000212465 antibody
      see all

    Anti-Aminoacylase 1 antibody 画像

    • Aminoacylase 1 antibody (ab54960) used in immunofluorescence at 10ug/ml on HeLa cells.
    • Aminoacylase 1 antibody (ab54960) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human malignant lymphoma, diffuse large B tissue.


    • Predicted band size : 46 kDa
      Aminoacylase 1 antibody (ab54960) at 1ug/lane + K-562 cell lysate at 25ug/lane.

    Anti-Aminoacylase 1 antibody (ab54960) 使用論文

    This product has been referenced in:
    • Wei X  et al. Proteomics-based identification of the tumor suppressor role of aminoacylase 1 in hepatocellular carcinoma. Cancer Lett 351:117-25 (2014). WB, IHC ; Human . Read more (PubMed: 24846301) »
    • Jin GZ  et al. A novel panel of biomarkers in distinction of small well-differentiated HCC from dysplastic nodules and outcome values. BMC Cancer 13:161 (2013). IHC-P ; Human . Read more (PubMed: 23537217) »

    See all 2 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab54960.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"