製品の概要

  • 製品名
    Amiloride hydrochloride
  • 製品の詳細
    eNaC blocker
  • 生理活性の詳細
    Epithelial sodium channel (eNaC) blocker. At higher concentrations, blocks the Na+/H+ exchange pathway. Also blocks transient reception potential cation (TRPC6 and TRPP3) channels.
  • 精製度
    > 99%

製品の特性

参考文献

This product has been referenced in:
  • Dai XQ  et al. Inhibition of TRPP3 channel by amiloride and analogs. Mol Pharmacol 72:1576-85 (2007). Read more (PubMed: 17804601) »
  • Alvarez de la Rosa D  et al. Structure and regulation of amiloride-sensitive sodium channels. Annu Rev Physiol 62:573-94 (2000). Read more (PubMed: 10845103) »
  • Frelin C  et al. Amiloride and its analogs as tools to inhibit Na+ transport via the Na+ channel, the Na+/H+ antiport and the Na+/Ca2+ exchanger. Biochimie 70:1285-90 (1988). Read more (PubMed: 2852509) »

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