製品の概要

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    Preservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度
    Protein A purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab16762 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500. Predicted molecular weight: 63 kDa.

ターゲット情報

  • 機能
    Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas.
  • 組織特異性
    Highest levels in breast, ovary, cervix, and uterus. Lower levels in lung, colon, and rectum. Differentially expressed in 56% of thyroid, 57% of pancreatic and 45% of stomach cancers.
  • 配列類似性
    Belongs to the immunoglobulin superfamily. AMIGO family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 6 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 LRRNT domain.
  • 細胞内局在
    Cell membrane. Nucleus. Associated with nucleus as well as plasma membrane. Restricted to somata of cerebellar as well as hippocampal neurons.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Adhesion molecule with Ig like domain 2 antibody
    • ALI 1 antibody
    • ALI1 antibody
    • Alivin 1 antibody
    • Alivin-1 antibody
    • Alivin1 antibody
    • AMGO2_HUMAN antibody
    • AMIGO 2 antibody
    • AMIGO-2 antibody
    • Amigo2 antibody
    • Amphoterin induced gene 2 antibody
    • Amphoterin induced protein 2 antibody
    • Amphoterin-induced gene and open reading frame 2 antibody
    • Amphoterin-induced protein 2 antibody
    • DEGA antibody
    • Differentially expressed in gastric adenocarcinoma antibody
    • Differentially expressed in gastric adenocarcinomas antibody
    • Transmembrane protein AMIGO 2 antibody
    • Transmembrane protein AMIGO2 antibody
    see all

プロトコール

参考文献

ab16762 has not yet been referenced specifically in any publications.

レビューと Q&A

Abcam has not validated the combination of species/application used in this Abreview.
Application
Immunohistochemistry (PFA perfusion fixed frozen sections)
Sample
Rat Tissue sections (Brain, medial habenula)
Specification
Brain, medial habenula
Username

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投稿 Nov 04 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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