製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to AMID
  • アプリケーション
    適用あり: ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide:

    GSQVSVESGALHC

    , corresponding to N terminal amino acids 2-13 of Human AMID.

  • ポジティブ・コントロール
    • Human Heart and Skeletal Muscle tissues

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファー
    pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 99% Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab115456 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/128000.
IHC-P Use a concentration of 4 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能
    Oxidoreductase, which may play a role in mediating a p53/TP53-dependent apoptosis response. Probable oxidoreductase that acts as a caspase-independent mitochondrial effector of apoptotic cell death. Binds to DNA in a sequence-independent manner. May contribute to genotoxin-induced growth arrest.
  • 組織特異性
    Detected in most normal tissues as two transcripts of 1.8 and 4.0 kb in length, respectively. Highly expressed in heart, moderately in liver and skeletal muscles, and expressed at low levels in placenta, lung, kidney, and pancreas. Both transcripts expressed following p53/TP53 induction. The shorter 1.8 kb transcript seems to be the major transcript in EB1 colon cancer cells.
  • 配列類似性
    Belongs to the FAD-dependent oxidoreductase family.
  • 細胞内局在
    Cytoplasm. Mitochondrion outer membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 5430437E11Rik antibody
    • aifm2 antibody
    • AIFM2_HUMAN antibody
    • AMID antibody
    • Apoptosis inducing factor (AIF) homologous mitochondrion associated inducer of death antibody
    • Apoptosis inducing factor (AIF) like mitochondrion associated inducer of death antibody
    • Apoptosis inducing factor mitochondrion associated 2 antibody
    • Apoptosis-inducing factor 2 antibody
    • Apoptosis-inducing factor homologous mitochondrion-associated inducer of death antibody
    • Apoptosis-inducing factor-like mitochondrion-associated inducer of death antibody
    • Cys51Stop antibody
    • HGNC11998 antibody
    • p53 responsive gene 3 antibody
    • p53 tumor suppressor antibody
    • p53-responsive gene 3 protein antibody
    • PRG3 antibody
    • TRP53 antibody
    • Tumor protein p53 antibody
    see all

画像

  • ab115456, at 4 µg/ml, staining AMID in formalin-fixed, paraffin-embedded Human Heart tissue by Immunohistochemistry, using a biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
  • ab115456, at 4 µg/ml, staining AMID in formalin-fixed, paraffin-embedded Human Skeletal Muscle tissue by Immunohistochemistry, using a biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

プロトコール

参考文献

ab115456 has not yet been referenced specifically in any publications.

レビューと Q&A

There are currently no Customer reviews or Questions for ab115456.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録