製品の概要

  • 製品名
    Anti-AMH antibody [5/6]
    AMH 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [5/6] to AMH
  • アプリケーション
    適用あり: IHC-Pmore details
  • 種交差性
    交差種: Mouse, Sheep, Human, Baboon
    交差が予測される動物種: Rat, Cow, Pig
  • 免疫原

    Synthetic peptide:

    VPTAYAGKLLISLSEERISAHHVPNMVATEC

    , corresponding to C terminal amino acids 527-557 of Human AMH.

  • ポジティブ・コントロール
    • Mouse ovary tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab24542 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/20 - 1/40. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 関連性
    Anti mullerian hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140kD disulphide linked precursor that is cleaved to release the mature 30kD homodimer. Originally classified as a foetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.
  • 細胞内局在
    Secreted
  • 参照データベース
  • 別名
    • Anti muellerian hormone antibody
    • MIF antibody
    • MIS antibody
    • Muellerian inhibiting factor antibody
    • Mullerian inhibiting substance antibody
    see all

画像

  • Ab24542, at a dilution of 1/20 to 1/40, staining formalin fixed paraffin embedded ovary tissue from a 25 day old mouse by Immunohystochemistry.

プロトコール

参考文献

This product has been referenced in:
  • Satie AP  et al. Excess type I interferon signaling in the mouse seminiferous tubules leads to germ cell loss and sterility. J Biol Chem 286:23280-95 (2011). IHC-P ; Mouse . Read more (PubMed: 21515676) »
  • Kevenaar ME  et al. Serum anti-mullerian hormone levels reflect the size of the primordial follicle pool in mice. Endocrinology 147:3228-34 (2006). Read more (PubMed: 16556768) »

See all 4 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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