製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to AMELX
  • アプリケーション
    適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Recombinant fragment
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    A synthetic peptide corresponding to N-terminal residues of mouse AMELX.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    Preservative: 0.1% Sodium Azide
    Constituents: 50% Glycerol, PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab54507 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 22 kDa. for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA Use at an assay dependent dilution.

ターゲット情報

  • 機能
    Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.
  • 関連疾患
    Defects in AMELX are the cause of amelogenesis imperfecta hypoplastic type 1 (AIH1) [MIM:301200]. AIH1 is a X-linked defect of dental enamel formation. Teeth have only a thin layer of enamel with normal hardness. The thinness of the enamel makes the teeth appear small.
  • 配列類似性
    Belongs to the amelogenin family.
  • 発生段階
    Transiently but abundantly expressed by ameloblasts during tooth development. Amelogenin is the predominant protein in developing dental enamel.
  • 細胞内局在
    Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AI1E antibody
    • AIH1 antibody
    • ALGN antibody
    • Amel antibody
    • Amelogenesis imperfecta 1 antibody
    • Amelogenin (amelogenesis imperfecta 1, X linked) antibody
    • Amelogenin (X chromosome) antibody
    • Amelogenin (X chromosome, amelogenesis imperfecta 1) antibody
    • Amelogenin antibody
    • Amelogenin X isoform antibody
    • Amelogenin, X linked antibody
    • AMELX antibody
    • AMELX_HUMAN antibody
    • Amg antibody
    • AMGL antibody
    • AMGX antibody
    • OTTHUMP00000022906 antibody
    • OTTHUMP00000022907 antibody
    • X isoform antibody
    see all

プロトコール

参考文献

This product has been referenced in:
  • Mazumder P  et al. Amelogenin-Ameloblastin Spatial Interaction around Maturing Enamel Rods. J Dent Res 95:1042-8 (2016). Read more (PubMed: 27146703) »
  • Lacruz RS  et al. Identification of novel candidate genes involved in mineralization of dental enamel by genome-wide transcript profiling. J Cell Physiol 227:2264-75 (2012). Read more (PubMed: 21809343) »

See all 2 Publications for this product

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