製品の概要

  • 製品名AMD 3465 hexahydrobromide
  • 製品の詳細
    Potent and selective CXCR4 antagonist
  • 生理活性の詳細Potent and selective CXCR4 antagonist. Shows 8-fold greater affinity than AMD 3100 (ab120718). Potent HIV entry inhibitor (IC50 = ~10 nM). Additionally mobilizes stem cells in vivo.
  • 精製度> 97%

製品の特性

  • 体系名N-[[4-(1,4,8,11-Tetraazacyclotetradec-1-ylmethyl)phenyl]methyl]-2-pyridinemethanamine hexahydrobromide
  • 分子量896.08
  • 構造式Chemical Structure
  • 分子式C24H38N6.6HBr
  • CAS 番号185991-07-5
  • PubChem 登録番号483559
  • 保存方法Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • 溶解性Soluble in water to 50 mM and in DMSO to 25 mM
  • 使用に関する注意

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES 線形表記Br.Br.Br.Br.Br.Br.C3NCCCNCCN(Cc2ccc(CNCc1ccccn1)cc2)CCCNC3
  • 由来

    Synthetic

    AMD 3465 hexahydrobromide (ab120809) 使用論文

    ab120809 has not yet been referenced specifically in any publications.

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