製品の概要

  • 製品名Anti-ALX4 antibody
    ALX4 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ALX4
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse
    交差が予測される動物種: Rat, Guinea pig, Cow, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 151-200 (EPELPPDSEP VGMDNSYLSV KETGAKGPQD RASAEIPSPL EKTDSESNKG) of Mouse ALX4 (NP_031468).

  • ポジティブ・コントロール
    • Mouse brain tissue lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab104298 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 44 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Transcription factor involved in skull and limb development. Plays an essential role in craniofacial development, skin and hair follicle development.
  • 組織特異性Expression is likely to be restricted to bone. Found in parietal bone.
  • 関連疾患Defects in ALX4 are the cause of parietal foramina 2 (PFM2) [MIM:609597]; also known as foramina parietalia permagna (FPP). PFM2 is an autosomal dominant disease characterized by oval defects of the parietal bones caused by deficient ossification around the parietal notch, which is normally obliterated during the fifth fetal month. PFM2 is also a clinical feature of Potocki-Shaffer syndrome.
    Defects in ALX4 are the cause of frontonasal dysplasia type 2 (FND2) [MIM:613451]. The term frontonasal dysplasia describes an array of abnormalities affecting the eyes, forehead and nose and linked to midfacial dysraphia. The clinical picture is highly variable. Major findings include true ocular hypertelorism; broadening of the nasal root; median facial cleft affecting the nose and/or upper lip and palate; unilateral or bilateral clefting of the alae nasi; lack of formation of the nasal tip; anterior cranium bifidum occultum; a V-shaped or widow's peak frontal hairline.
    Involved in Potocki-Shaffer syndrome (PSS) [MIM:601224]. PSS is a contiguous gene syndrome caused by deletion of the 11p11.2 region.
  • 配列類似性Belongs to the paired homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Alx4 antibody
    • ALX4_HUMAN antibody
    • Aristaless like homeobox 4 antibody
    • FND2 antibody
    • FPP antibody
    • homeobox protein aristaless like 4 antibody
    • Homeobox protein aristaless-like 4 antibody
    • homeodomain transcription factor ALX4 antibody
    • KIAA1788 antibody
    • PFM1 antibody
    • PFM2 antibody
    see all

Anti-ALX4 antibody 画像

  • Anti-ALX4 antibody (ab104298) at 1 µg/ml + Mouse brain tissue lysate at 10 µg

    Predicted band size : 44 kDa

Anti-ALX4 antibody (ab104298) 使用論文

ab104298 has not yet been referenced specifically in any publications.

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