製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to ALS2CL
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide from N terminal residues of Human ALS2CL protein (NM_147129.3).

  • ポジティブ・コントロール
    • Mouse kidney lysate.

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab119937 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 108 kDa (predicted molecular weight: 22, 23, 53, 85, 108 kDa).

ターゲット情報

  • 機能
    Acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase. Regulates the ALS2-mediated endosome dynamics.
  • 組織特異性
    Expressed in heart and kidney.
  • 配列類似性
    Contains 8 MORN repeats.
    Contains 1 VPS9 domain.
  • 細胞内局在
    Cytoplasm. Distributed onto the vesicular compartments in the cytoplasm with strong punctated staining. Colocalizes with RAB5A onto the vesicular/membranous compartments in the cytoplasm, particularly to the leading edges of the cells.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AL2CL_HUMAN antibody
    • ALS2 C-terminal like antibody
    • ALS2 C-terminal-like protein antibody
    • Als2cl antibody
    • DKFZp686I0110 antibody
    • DKFZp686P238 antibody
    • FLJ36525 antibody
    • MGC129698 antibody
    • RN49018 antibody
    see all

画像

プロトコール

参考文献

ab119937 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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