Anti-alpha+beta SNAP 抗体 [6B7-3] (ab69742)

製品の概要

  • 製品名Anti-alpha+beta SNAP antibody [6B7-3]
    alpha+beta SNAP 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [6B7-3] to alpha+beta SNAP
  • 特異性This antibody detects a doublet of 35 and 36 kDa proteins, corresponding to the apparent molecular mass of alpha + beta SNAP.
  • アプリケーション適用あり: WB, IPmore details
  • 種交差性
    交差種: Mouse, Rat, Hamster, Cow, Dog, Human
  • 免疫原

    Recombinant full length bovine alpha SNAP protein expressed in E coli

  • ポジティブ・コントロール
    • Rat brain tissue extract and mouse brain tissue extract.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab69742 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1.5 µg/ml. Predicted molecular weight: 38 kDa.
IP Use at an assay dependent dilution.

ターゲット情報

  • 関連性Alpha, beta and gamma SNAPs, also known as soluble NSF attachment proteins, have apparent molecular weights on SDS PAGE of 35, 36 and 39 kDa, respectively. SNAP proteins mediate the association of NSF to membranes during vesicle fusion reaction, and play a prominent role in synaptic vesicle fusion. In addition, beta SNAP interacts with synaptotagmin and may be involved in calcium regulated exocytosis. SNAP was identified as being required for vesicle fusion in intra Golgi transport reaction in vitro. Alpha SNAP mediates the association of NSF to membranes during vesicle fusion reaction, and plays a prominent role and in synaptic vesicle fusion. Together with synaptotagmin and NSF, alpha SNAP modulates the interaction of SNAP25, VAMP, and syntaxin in, an ATP dependent manner, to form a complex with a sedimentation coefficient of 20 S. This complex may represent an intermediate involved in synaptic vesicle docking and fusion.
  • 細胞内局在Cytoplasmic peripheral membrane protein.
  • 参照データベース
  • 別名
    • Alpha soluble NSF attachment protein antibody
    • Beta soluble NSF attachment protein antibody
    • N ethylmaleimide sensitive factor attachment protein alpha antibody
    • N ethylmaleimide sensitive factor attachment protein beta antibody
    • NAPA antibody
    • NAPB antibody
    • SNAP Alpha antibody
    • SNAP Beta antibody
    • SNAPA antibody
    • SNAPB antibody
    • SNARE antibody
    • Soluble NSF attachment protein antibody
    see all

Anti-alpha+beta SNAP antibody [6B7-3] (ab69742) 使用論文

ab69742 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"