製品の概要

  • 製品名Anti-Alpha B Crystallin (phospho S19) antibody
    Alpha B Crystallin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Alpha B Crystallin (phospho S19)
  • アプリケーション適用あり: ICC/IF, IHC-P, WBmore details
  • 種交差性
    交差種: Mouse, Rat, Cow, Human
    交差が予測される動物種: Sheep, Rabbit, Hamster, Pig, Cynomolgus Monkey
  • 免疫原

    Synthetic peptide corresponding to Human Alpha B Crystallin aa 14-25.
    Sequence: FFPFHSpPSRLFD

  • ポジティブ・コントロール
    • Immunofluorescence staining of phospho-alpha-B crystallin (Ser19) in U373 MG cells results in cytoplasmic staining.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab5597 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use a concentration of 5 µg/ml.
IHC-P Use a concentration of 10 µg/ml.
WB Use a concentration of 0.5 µg/ml. Detects a band of approximately 20 kDa.

ターゲット情報

  • 機能May contribute to the transparency and refractive index of the lens.
  • 組織特異性Lens as well as other tissues.
  • 関連疾患Defects in CRYAB are the cause of myofibrillar alpha-B crystallin-related (MFM-CRYAB) [MIM:608810]. A neuromuscular disorder that results in weakness of the proximal and distal limb muscles, weakness of the neck, velopharynx and trunk muscles, hypetrophic cardiomyopathy, and cataract in a subset of patients.
  • 配列類似性Belongs to the small heat shock protein (HSP20) family.
  • 細胞内局在Cytoplasm. Nucleus. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AACRYA antibody
    • Alpha B crystallin antibody
    • Alpha crystallin B chain antibody
    • Alpha(B)-crystallin antibody
    • Alpha-crystallin B chain antibody
    • CRYA2 antibody
    • Cryab antibody
    • CRYAB_HUMAN antibody
    • Crystallin alpha B antibody
    • Crystallin alpha polypeptide 2 antibody
    • CTPP2 antibody
    • Heat shock 20 kD like protein antibody
    • Heat shock protein beta 5 antibody
    • Heat shock protein beta-5 antibody
    • HspB5 antibody
    • Renal carcinoma antigen NY REN 27 antibody
    • Renal carcinoma antigen NY-REN-27 antibody
    • Rosenthal fiber component antibody
    see all

Anti-Alpha B Crystallin (phospho S19) antibody 画像

  • All lanes : Anti-Alpha B Crystallin (phospho S19) antibody (ab5597) at 0.5 µg/ml

    Lane 1 : phospho-alpha-B crystallin (Ser19)
    Lane 2 : unphosphorylated alpha-B crystallin


    Observed band size : 20 kDa (why is the actual band size different from the predicted?)

Anti-Alpha B Crystallin (phospho S19) antibody (ab5597) 使用論文

This product has been referenced in:
  • Lambrecht S  et al. Differential expression of alphaB-crystallin and evidence of its role as a mediator of matrix gene expression in osteoarthritis. Arthritis Rheum 60:179-88 (2009). WB ; Human . Read more (PubMed: 19116904) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"