Anti-alpha Adducin 抗体 [EP734Y] (ab40760)

製品の概要

  • 製品名Anti-alpha Adducin antibody [EP734Y]
    alpha Adducin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EP734Y] to alpha Adducin
  • アプリケーション適用あり: WB, IHC-P, ICC/IFmore details
    適用なし: Flow Cyt or IP
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    A synthetic peptide corresponding to residues in the C-term of human Adducin was used as immunogen.

  • ポジティブ・コントロール
    • HeLa cell lysate, human lung (IHC-p).
  • 特記事項

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab40760 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/5000 - 1/50000. Detects a band of approximately 120 kDa (predicted molecular weight: 120 kDa).
IHC-P 1/250 - 1/500.
ICC/IF 1/250 - 1/500.
  • 追加情報Is unsuitable for Flow Cyt or IP.
  • ターゲット情報

    • 機能Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin.
    • 組織特異性Expressed in all tissues. Found in much higher levels in reticulocytes than the beta subunit.
    • 配列類似性Belongs to the aldolase class II family. Adducin subfamily.
    • ドメインEach subunit is comprised of three regions: a NH2-terminal protease-resistant globular head region, a short connecting subdomain, and a protease-sensitive tail region.
    • 細胞内局在Cytoplasm > cytoskeleton. Cell membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • ADD A antibody
      • ADD1 antibody
      • ADDA antibody
      • ADDA_HUMAN antibody
      • Adducin 1 (alpha) antibody
      • Alpha adducin antibody
      • Alpha-adducin antibody
      • Erythrocyte adducin alpha subunit antibody
      • Erythrocyte adducin subunit alpha antibody
      • MGC3339 antibody
      • MGC44427 antibody
      • OTTHUMP00000151163 antibody
      • OTTHUMP00000151164 antibody
      • OTTHUMP00000151165 antibody
      • OTTHUMP00000218664 antibody
      • OTTHUMP00000218665 antibody
      see all

    Anti-alpha Adducin antibody [EP734Y] 画像

    • Anti-alpha Adducin antibody [EP734Y] (ab40760) at 1/50000 dilution + HeLa cell lysate at 10 µg

      Predicted band size : 120 kDa
      Observed band size : 120 kDa
    • ab40760 (1/250), staining human lung by immunohistochemistry, paraffin embedded tissue.
    • ab40760, (1/250) staining HeLa cells by immunofluorescence.

    Anti-alpha Adducin antibody [EP734Y] (ab40760) 使用論文

    ab40760 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your reply.

    I have had the opportunity to view the exact immunogen sequence used for this product. While the exact information is considered proprietary, I can confirm that this immunogen is based on a region spanning aa 710 thr...

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    Sorry for my error. The correct statement is:
    The adducin alpha antibody is predicted to cross-react with beta- and gamma-adducin. The immunogen shares 100% identity with both beta- and gamma-adducin, respectively.

    I hope this is helpful...

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    Thank you for contacting us.

    I have collected some data for you regarding these products as requested.
    Regarding ab40760; this is predicted to cross-react with Beta-Adducin and Gamma-Adducin, based on sequence analysis. The immunogen sha...

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    The beta-adducin antibody is likely (although not guaranteed) to cross-react with alpha- or gamma- adducin. The immunogen shares 100% and 94% identity with alpha- and gamma-adducin, respectively.
    I hope this is helpful. Please contact me again if ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"