Anti-alpha 2 Macroglobulin 抗体 (Biotin) (ab7338)

製品の概要

  • 製品名
    Anti-alpha 2 Macroglobulin antibody (Biotin)
    alpha 2 Macroglobulin 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to alpha 2 Macroglobulin (Biotin)
  • 標識
    Biotin
  • アプリケーション
    適用あり: Immunomicroscopy, IP, WB, Dot blot, ELISA, IHC-Frmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Alpha-2-Macroglobulin [Human Plasma]

  • 特記事項

    Biotinamidocaproate N-Hydroxysuccinimide Ester (BAC) Biotin/Protein Ratio: 10-20 BAC molecules per rabbit IgG molecule.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    pH: 7.60
    Preservative: 0.01% Sodium azide
    Constituents: 0.88% Sodium chloride, 1% BSA, 0.42% Potassium phosphate
  • Concentration information loading...
  • 精製度
    IgG fraction
  • 特記事項(精製)
    This product is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab7338 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Immunomicroscopy
IP
WB
Dot blot
ELISA
IHC-Fr
  • 追加情報
    Immunoblotting (western or dot blot)
    ELISA (1:9,000 to 1:36,000)
    Immunohistochemistry
    Immunomicroscopy
    as well as other antibody based assays using streptavidin or avidin conjugates requiring lot-to-lot consistency.
  • ターゲット情報

    • 機能
      Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
    • 組織特異性
      Secreted in plasma.
    • 配列類似性
      Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
    • 発生段階
      Contrary to the rat protein, which is an acute phase protein, this protein is always present at high levels in circulation.
    • 細胞内局在
      Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • A2m antibody
      • A2MG_HUMAN antibody
      • Alpha 2 M antibody
      • Alpha 2M antibody
      • Alpha-2-M antibody
      • Alpha-2-macroglobulin antibody
      • C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5 antibody
      • CPAMD5 antibody
      • DKFZp779B086 antibody
      • FWP007 antibody
      • S863 7 antibody
      see all

    参考文献

    This product has been referenced in:
    • Jensen PE  et al. Significantly increased fractions of transformed to total alpha2-macroglobulin concentrations in plasma from patients with multiple sclerosis. Biochim Biophys Acta 1690:203-7 (2004). ELISA . Read more (PubMed: 15511627) »

    See 1 Publication for this product

    レビューと Q&A

    Thank you for your enquiry. As these 4 antibodies are all polyclonal antibodies, each will recognize multiple epitopes. If you have any more questions, please do contact us again.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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