製品の概要

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab92840 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報ELISA: Use at a concentration of 5 µg/ml (for coating) or 0.2 µg/ml (for detection).
    WB: Use at a concentration of 0.2 µg/ml. Predicted molecular weight: 164 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
    • 組織特異性Secreted in plasma.
    • 配列類似性Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
    • 発生段階Contrary to the rat protein, which is an acute phase protein, this protein is always present at high levels in circulation.
    • 細胞内局在Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • A2m antibody
      • A2MG_HUMAN antibody
      • Alpha 2 M antibody
      • Alpha 2M antibody
      • Alpha-2-M antibody
      • Alpha-2-macroglobulin antibody
      • C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5 antibody
      • CPAMD5 antibody
      • DKFZp779B086 antibody
      • FWP007 antibody
      • S863 7 antibody
      see all

    Anti-alpha 2 Macroglobulin antibody (ab92840) 使用論文

    ab92840 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab92840.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"