Anti-alpha 1 Glycine Receptor 抗体 (ab55057)

製品の概要

  • 製品名Anti-alpha 1 Glycine Receptor antibody
    alpha 1 Glycine Receptor 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to alpha 1 Glycine Receptor
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Recombinant Fragment
    交差が予測される動物種: Human
  • 免疫原

    Recombinant fragment: IWKPDLFFAN EKGAHFHEIT TDNKLLRISR NGNVLYSIRI TLTLACPMDL KNFPMDVQTC IMQLESFGYT MNDLIFEWQE QGAVQVADGL TLPQFILKEE , corresponding to amino acids 121-221 of Human alpha 1 Glycine Receptor

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab55057 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).
    • 関連疾患Defects in GLRA1 are a cause of startle disease (STHE) [MIM:149400]; also known as hereditary hyperekplexia or congenital stiff-person syndrome. STHE is a genetically heterogeneous neurologic disorder characterized by muscular rigidity of central nervous system origin, particularly in the neonatal period, and by an exaggerated startle response to unexpected acoustic or tactile stimuli. Inheritance can be autosomal dominant or recessive.
    • 配列類似性Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA1 sub-subfamily.
    • 細胞内局在Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • GLRA1 antibody
      • GLRA1_HUMAN antibody
      • Glycine receptor 48 kDa subunit antibody
      • Glycine receptor alpha 1 antibody
      • Glycine receptor strychnine-binding subunit antibody
      • Glycine receptor subunit alpha-1 antibody
      • Glycine receptor, alpha 1 subunit antibody
      • HKPX1 antibody
      • STHE antibody
      see all

    Anti-alpha 1 Glycine Receptor antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab55057 alpha 1 Glycine Receptor antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa.

      This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Anti-alpha 1 Glycine Receptor antibody (ab55057) 使用論文

    ab55057 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab55057.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"