Anti-alpha 1 Glycine Receptor 抗体 (ab26134)

製品の概要

  • 製品名Anti-alpha 1 Glycine Receptor antibody
    alpha 1 Glycine Receptor 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to alpha 1 Glycine Receptor
  • 特異性ab26134 recognises Glycine receptor alpha-1 chain precursor (GLRA1).
  • アプリケーション適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow, Dog, Zebrafish
  • 免疫原

    Synthetic peptide derived from a region between residues 178 - 227 of human Glycine Receptor alpha 1.

    .

  • ポジティブ・コントロール
    • Raji cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab26134 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/62500.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 51 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).
  • 関連疾患Defects in GLRA1 are a cause of startle disease (STHE) [MIM:149400]; also known as hereditary hyperekplexia or congenital stiff-person syndrome. STHE is a genetically heterogeneous neurologic disorder characterized by muscular rigidity of central nervous system origin, particularly in the neonatal period, and by an exaggerated startle response to unexpected acoustic or tactile stimuli. Inheritance can be autosomal dominant or recessive.
  • 配列類似性Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA1 sub-subfamily.
  • 細胞内局在Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • GLRA1 antibody
    • GLRA1_HUMAN antibody
    • Glycine receptor 48 kDa subunit antibody
    • Glycine receptor alpha 1 antibody
    • Glycine receptor strychnine-binding subunit antibody
    • Glycine receptor subunit alpha-1 antibody
    • Glycine receptor, alpha 1 subunit antibody
    • HKPX1 antibody
    • STHE antibody
    see all

Anti-alpha 1 Glycine Receptor antibody 画像

  • Anti-alpha 1 Glycine Receptor antibody (ab26134) at 1 µg/ml + Raji cell lysate

    Predicted band size : 51 kDa

Anti-alpha 1 Glycine Receptor antibody (ab26134) 使用論文

ab26134 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry regarding our antibody to alpha 1 glycine receptor. To my knowledge, there is no experimental data on whether this antibody will also recognise alpha2 glysine receptor. I have done a BLAST sequence alignment analogy search, a...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"